PUBLICATIONs

Manuscripts

2012

Thompson, C.M., D.M. Proctor, M. Suh, L.C. Haws, C.D. Hebert, J.F. Mann, H.G. Shertzer, J.G. Hixon and M.A. Harris. Comparison of the Effects of Hexavalent Chromium in the Alimentary Canal of F344 Rats and B6C3F1 Mice Following Exposure in Drinking Water: Implications for Carcinogenic Modes of Action. Toxicol Sci. 125(1):79-90.

2011

Bogen K.T., Brorby G.P., Berman D.W., Sheehan P.J., Floyd M.  Measuring mixed cellulose ester (MCE) filter mass under variable humidity conditions.  Annals of Occupational Hygiene. 55(5)485-494.

Brorby G.P., Sheehan P.J., Berman D.W., Bogen K.T., Holm S.E.  Potential artifacts associated with historical preparation of joint compound samples and reported airborne asbestos concentrations.  Journal of Occupational and Environmental Hygiene. 8(5):271–278.

Carakostas, M. 'Long-term feeding effects of stevioside sweetener on some toxicological parameters of growing rats'. Journal of Applied Toxicology. 31(6):595-596.

Gujral, J.S., D.M. Proctor, S.H. Su, and J.M. Fedoruk. 2011. Water Adherence Factors for Human Skin. Risk Analysis. 31(8): 1271-1280.

Kopec, A.K., Kim, S., Forgacs, A.L., Zacharewski, T.R., Proctor, D.M., Harris, M.A., Haws, L.C, Thompson, C.M. (accepted) Genome-wide gene expression effects in B6C3F1 mouse intestinal epithelia following 7 and 90 days of exposure to hexavalent chromium in drinking water. Toxicology and Applied Pharmacology. 2011 Dec 1. [Epub ahead of print].

Rowlands J.C., J.D. Urban, D.S. Wikoff, R.A. Budinsky. An evaluation of single nucleotide polymorphisms in the human aryl hydrocarbon receptor-interacting protein (AIP) gene. Drug Metab Pharmacokinet. 26(4): 431-439.

Sheehan P.J., Brorby G.P., Berman D.W., Bogen K.T., Holm S.E.  Chamber for testing asbestos-containing products:  Validation and testing of a re-created chrysotile-containing joint compound.  Annals of Occupational Hygiene. 55(7):797-809.

Thompson, C.M., D.M. Proctor, L.C. Haws, C.D. Hebert, S.D. Grimes, H.G. Shertzer, A.K. Kopec, J.G. Hixon, T.R. Zacharewski and M.A. Harris. Investigation of the Mode of Action Underlying the Tumorigenic Response Induced in B6C3F1 Mice Exposed Orally to Hexavalent Chromium. Toxicol Sci. 123(1): 58-70.

Thompson, C.M. and R.C. Grafström. Considerations for the implausibility of leukemia induction by formaldehyde. Toxicol Sci. 120(1):230-2.

Thompson, C.M., L.C. Haws, M.A. Harris, N.M. Gatto and D.M. Proctor. Application of the U.S. EPA Mode of Action Framework for Purposes of Guiding Future Research: A Case Study Involving the Oral Carcinogenicity of Hexavalent Chromium. Toxicol Sci. 119(1): 20-40.

Tichomirowa, M.A., A. Bariler, A.F. Daly, M.-L. Jaffrain-Rea, C.L. Ronchi, M. Yaneva, J.D. Urban, P. Petrossians, A.P. Elenkova, A. Tabarin, R. Desailloud, D. Maiter, T. Schürrmeyer, R. Cozzi, M. Theodoropoulou, C. Sievers, I. Bernabeu, L.A. Naves, O. Chabre, C. Fajardo Montañana, V. Hana, G. Halaby, B. Delemer, J.I. Labarta, E. Sonnet, A. Ferrandez, M.T.s. Hagelstein, P. Caron, G.K. Stalla, V. Bours, S. Zacharieva, A. Spada, T. Brue and A. Beckers. 2011. High Prevalence of AIP Gene Mutations Following Focused Screening in Young Patients with Sporadic Pituitary Macroadenomas. Eur J Endocrinol. 165(4): 509-515.

Urban, J., Budinsky, R., Rowlands, J. 2011. An evaluation of single nucleotide polymorphisms in the human heat shock protein 90kDa alpha and beta isoforms. Drug Metab Pharmacokinet. 2011 Dec 20. [Epub ahead of print].

Urban, J.D., J.C. Rowlands, R.A. Budinsky. 2011. Single nucleotide polymorphisms in the human aryl hydrocarbon receptor nuclear translocator (ARNT) gene. Drug Metab Pharmacokinet. 2011 Aug 9. [Epub ahead of print].

2010

Birnbaum, L.S. and D. Staskal-Wikoff. 5th International PCB Workshop--summary and implications.Environ Int. 36(8): 814-8.

Gatto, N.M., M.A. Kelsh, D.H. Mai, M. Suh and D.M. Proctor. Occupational exposure to hexavalent chromium and cancers of the gastrointestinal tract: a meta-analysis. Cancer Epidemiol. 34(4):388-99.

Rowlands, C.J., D.F. Staskal, B. Gollapudi and R. Budinsky. The Human AHR: identification of single nucleotide polymorphisms from six ethnic populations. Pharmacogenet Genomics. 20(5):283-90.

Sheehan P., Bogen K.T., Hicks J., Goswami E., Brorby G., Lau E., Ott B.  Benzene inhalation of parts washers:  New estimates based on measures of occupational exposure to solvent coaromatics.  Risk Analysis. 30(8):1249–1267.

Tachovsky, J.A., J.D. Urban, D.S. Wikoff, L.C. Haws and M.A. Harris. Reduction of a large fish tissue analyte database: identifying and assessing data specific to a remediation site for risk assessment application. Chemosphere. 80(5):481-8.

Thompson, C.M., R. Ceder and R.C. Grafström. Formaldehyde dehydrogenase: beyond phase I metabolism. Toxicol Lett. 193(1):1-3.

Urban, J., J.A. Tachovsky, L. Haws, D. Wikoff Staskal, and M. Harris. 2010. Response to Mugdan et al.’s comment on Urban et al. “Assessment of Human Health Risks Posed by Consumption of Fish from the Lower Passaic River, New Jersey.” Science of the Total Environment. 408(6):1468-1470.

Urban, J.D., J.A. Tachovsky, L.C. Haws, D.F. Staskal, and M.A. Harris. Response to Buchanan et al.’s comment on Urban et al. “Assessment of Human Health Risks Posed by Consumption of Fish from the Lower Passaic River, New Jersey.” Science of the Total Environment. 408(8):2004-2007.

2009

DeSesso, J.M., R.E. Watson, C.L. Keen, K.P. Hazelden, L.C. Haws, and A.A. Li. Analysis and integration of developmental neurotoxicity and ancillary data into risk assessment: a case study of dimethoate. J Toxicol Environ Health A.. 72(2):94-109.

Driscoll, S.K., M.E. McArdle, M.H. Plumlee and D. Proctor. Evaluation of hexavalent chromium in sediment pore water of the Hackensack River, New Jersey, USA. Environ Toxicol Chem. 29(3):617-20.

Menzie, C.A., L.M. Ziccardi, Y.W. Lowney, A. Fairbrother, S.S. Shock, J.S. Tsuji, D. Hamai, D. Proctor, et al. Importance of considering the framework principles in risk assessment for metals. Environ Sci Technol. 43(22): 8478-82.

Scott, L.L.F., Staskal, D.F., Williams ES, Luksemburg WJ, Urban JD, Nguyen LM, Haws LC, Birnbaum LS, Paustenbach DJ, Harris MA. 2009. Levels of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls in southern Mississippi catfish and estimation of potential health risks. Chemosphere. 74(7):1002-10.

Thompson, C.M. and R.C. Grafstrom. Commentary: mechanistic considerations for associations between formaldehyde exposure and nasopharyngeal carcinoma. Environ Health. 8:53.

Thompson, C.M., Sonawane, B., and Grafström, R.C. The Ontogeny, Distribution and Regulation of Alcohol Dehydrogenase 3: Implications for Pulmonary Physiology. Drug Metabolism and Disposition. 37(8): 1565-71.

2008

Carakostas, M.C., L.L. Curry, A.C. Boileau and D.J. Brusick. Overview: the history, technical function and safety of rebaudioside A, a naturally occurring steviol glycoside, for use in food and beverages.Food Chem Toxicol. 46(Suppl 7): S1-S10.

Donovan, E., K. Unice, J.D. Roberts, M. Harris, and B. Finley. 2008. Risk of Gastrointestinal Disease Associated with Exposure to Pathogens in the Water of the Lower Passaic River. Appl Environ Microbiol. 74:994-1003.

Donovan, E.P., D.F. Staskal, K.M. Unice, J.D. Roberts, L.C. Haws, B.L. Finley, and M.A. Harris. 2008. Risk of Gastrointestinal Disease Associated with Exposure to Pathogens in the Sediments of the Lower Passaic River. Appl Environ Microbiol. 74:1004-1018.

Haws, L.C., J.A. Tachovsky, E.S Williams, L.F. Scott, D. Paustenbach, and M. Harris. 2008. Assessment of Potential Human Health Risks Posed by Benzene in Beverages, J. Food Sci. 73(4):T33-41.

Richardson, V.M., D.F. Staskal, D.G. Ross, J.J. Diliberto, M.J. Devito, and L.S. Birnbaum. 2008. Possible mechanisms of thyroid hormone disruption in mice by BDE 47, a major polybrominated diphenyl ether congener. Toxicol Appl Pharmacol. 226(3):244-50.

Scott, L.L.F., M. Harris, K.M. Unice, P. Scott, L.M. Nguyen, L.C. Haws, and D. Paustenbach. 2008. Addendum to: Evaluation of PCDD/F and dioxin-like PCB serum concentration data from the 2001-2002 National Health and Nutrition Examination Survey of the United States population. J Exp Sci Env Epidemiol. 18(5):524-32.

Scott, P.K. and D. Proctor. Soil suspension/dispersion modeling methods for estimating health-based soil cleanup levels of hexavalent chromium at chromite ore processing residue sites. J Air Waste Manag Assoc. 58(3): 384-403.

Staskal, D.F., L.L.F. Scott, L.C. Haws, W.J. Luksemburg, L.S. Birnbaum, L.M. Nguyen, J.D. Urban, E.S. Williams, D.J. Paustenbach, and M.A. Harris. Assessment of Polybrominated diphenyl ether Exposures and Health Risks Associated with Consumption of Southern Mississippi Catfish. Environ Sci Technol. 42(17): 6755-61.

Urban, J.D., J.A. Tachovsky, D.F. Staskal, L.C. Haws, and M.A. Harris. Assessment of Human Health Risks Posed by Consumption of Fish from the Lower Passaic River, New Jersey. Sci Total Environ. 408(2): 209-24.

2007

Ferriby, L.L., J.S. Knutsen, M. Harris, K.M. Unice, P. Scott, P. Nony, L.C. Haws, and D. Paustenbach. 2007. Evaluation of PCDD/F and dioxin-like PCB serum concentration data from the 2001-2002 National Health and Nutrition Examination Survey of the United States Population. J Exp Sci Env Epidemiol. 17: 358-371.

Proctor DM, Gatto NM, Hong SJ, Allamneni KP. Mode-of-action framework for evaluating the relevance of rodent forestomach tumors in cancer risk assessment. Toxicol Sci. 98(2):313–326.

Reedy, R. C., B. R. Scanlon, J. P. Nicot, and J.A. Tachovsky. 2007. Unsaturated Zone Arsenic Distribution and Implications for Groundwater Contamination. Environ Sci Technol. 41(20):6914-6919.

Scanlon, B. R., R. C. Reedy, and J.A. Tachovsky. 2007. Semiarid unsaturated zone chloride profiles: Archives of past land use change impacts on water resources in the southern High Plains, United States. Water Res Res. 43(W06423):13PP.

Urban, J.D., W.P. Clarke, M. von Zastrow, B. Kobilka, D.E. Nichols, H. Weinstein, J.A. Javitch, B.L. Roth, A. Christopoulos, P.M. Sexton, K.J. Miller, M. Spedding, and R.B. Mailman. 2007. Functional selectivity and classical concepts of quantitative pharmacology. J. Pharmacol Exp Therap. 320 (1): 1-13.

Urban, J.D., G. Vargas, M. von Zastrow, and R.B. Mailman. 2007. Aripiprazole has functionally selective actions at D2 receptor-mediated signaling pathways. Neuropsychopharmacology. 32 (1): 67-77.

2006

Becker DS, Long ER, Proctor DM, Ginn TC. Toxicity and bioavailability of chromium in sediments associated with chromite ore processing residue. 2006. Environ Toxicol Chem. 25(10):2576–2583.

Haws, L.C., S. Su, M. Harris, M. DeVito, N. Walker, W. Farland, B. Finley, and L. Birnbaum. 2006. Development of a refined database of mammalian relative potency estimates for dioxin-like compounds. Toxicol Sci. 89(1):4-30.

Paustenbach, D.J., K. Fehling, P. Scott, M. Harris, and B. Kerger. 2006. Identifying a soil clean-up criteria for dioxin in urban residential soils: How have 20 years of research and risk assessment experience affected the analysis? J Toxicol Environ Health, Part B. 9:87-145.

Staskal, D.F., J.J. Diliberto and L.S. Birnbaum. 2006. Impact of repeated exposure on the toxicokinetics of BDE 47 in mice. Toxicol Sci. 89:380-5.

Staskal, D.F., J.J. Diliberto, and L.S. Birnbam. 2006. Disposition of BDE 47 in developing mice. Toxicol Sci. 90:309-16.

Staskal, D.F., H. Hakk, D. Bauer, J.J. Diliberto, and L.S. Birnbam. 2006. Toxicokinetics of Polybrominated diphenyl ether congeners 47, 99, 100, and 153 in mice. Toxicol Sci. 94:28-37.

Van den Berg, M., L. Birnbaum, M. Denison, M. De Vito, W. Farland, M. Feeley, H. Fiedler, H. Hakansson, A. Hanberg, L.C. Haws, M. Rose, S. Safe, D. Schrenk, C. Tohyama, A. Tritscher, J. Tuomisto, M. Tysklind, N. Walker, and R.E. Peterson. 2006. The 2005 World Health Organization Reevaluation of Human and Mammalian Toxic Equivalency Factors for Dioxins and Dioxin-Like Compounds. Toxicol Sci. 93(2):223-241.

2005

Staskal, D.F., J.J. Diliberto, M.J. DeVito and L.S. Birnbaum. 2005. Inhibition of Human and Rat CYP1A2 by TCDD and Dioxin-like Chemicals. Toxicol Sci. 84: 225-31.

Staskal, D.F., J.J. Diliberto, M.J. DeVito, and L.S. Birnbaum. 2005. Toxicokinetics of BDE 47 in Female Mice: Effects of Dose, Route of Exposure, and Time. Toxicol Sci. 83: 215-23.

2004

Birnbaum, L.S., and D.F. Staskal. 2004. Brominated Flame Retardants: Cause for Concern? Environ Health Perspect. 112: 9-17.

Gay, E.A., J.D. Urban, D.E. Nichols, G.S. Oxford, and R.B. Mailman. 2004. Functional selectivity of D2 receptor ligands in a Chinese hamster ovary hD2L cell line: evidence for induction of ligand-specific receptor states. Mol Pharmacol. 66 (1): 97 - 105.

Proctor DM, Panko JP, Liebig EW, Paustenbach, DJ. Estimating historical occupational exposure to airborne hexavalent chromium in a chromate production plant: 1940–1972. 2004. Occup Environ Hyg. 1:752–767.

Schecter, A., O. Papke, K.C. Tung, D.F. Staskal, and L. Birnbaum. 2004. Polybrominated diphenyl ether contamination of United States food. Environ Sci Technol. 38(20): 5306-11.

2003

Birnbaum, L.S., D.F. Staskal, and J.J. Diliberto. 2003. Health effects of polybrominated dibenzo-p-dioxins (PBDDs) and dibenzofurans (PBDFs). Environ Inter. 29: 855-860.

Crump C, Crump KS, Hack E, Luippold RS, Mundt KA, Panko JP, Liebig EW, Paustenbach DJ, Proctor DM. Dose-response and risk assessment of airborne hexavalent chromium and lung cancer mortality. 2003. Risk Anal. 23(6):1155−1171.

Luippold RS, Mundt KA, Austin RP, Liebig E, Panko JP, Crump C, Crump K, Proctor DM. Lung cancer mortality among chromate workers. 2003. Occup Environ Med. 60:451−457.

Proctor, D., J. Panko, E. Liebig, K. Mundt, M. Buczynski, R. Barnhart, M. Harris, R. Morgan, B. Finley, and D. Paustenbach. 2003. Workplace concentrations of airborne hexavalent chromium for the Painesville, Ohio chromate production plant. Appl Occ Environ Hyg J. 18(6):430-449.

Scott, P., J. Petura, and M. Harris. Derivation of a liquid to solid ratio for ASTM method D3987 85 for soils containing chromite ore processing residue using selected unsaturated zone models. Soil Sed Contam. 12(4):443-480.

2002

Grant, R.L., R. Rodriguez, C.S. Hofelt, and L.C. Haws. 2002. Shortcomings in USEPA's approach for predicting risk due to consumption of animal food products impacted by air emissions from hazardous waste combustion facilities: a case study involving phthalates. Human Ecol Risk Assess. 8(5):1137-1154.

2001

Hofelt, C.S., M. Honeycutt, J.T. McCoy, and L.C. Haws. 2001. Development of a metabolism factor for polycyclic aromatic hydrocarbons for use in multipathway risk assessments for hazardous waste combustion facilities. Reg Toxicol Pharmacol. 33:60-65.

2000

Finley, B.L., D.M. Proctor, M. Harris, and J.F. Fowler. 2000. Letter to the editor. American J Contact Derm. 123-125.

1997

Costa, M., A. Zhitkovich, M. Harris, D. Paustenbach, and M. Gargas. 1997. DNA-Protein crosslinks produced by various chemicals in cultured human lymphocytes. J Toxicol Environ Health.

Scott, P., B. Finley, M. Harris, and D. Rabbe. 1997. Determination of background airborne hexavalent chromium concentrations in industrial areas. J Air Waste Manage. Assoc. 47:592-600.

1996

Ramu, K., Perry, C.S., Ahmed, T., Pakenham, G., and Kehrer, J.P. Studies on the basis for the toxicity of acrolein mercapturates. Toxicology and Applied Pharmacology. 140(2):487-498.

Sauers, L. and C.Perry.. Regulatory affairs - a growing opportunity for toxicologists. SOT Communiqué, May/June 1996.

1995

Perry, C.S., Liu, X.L., Lund, L.G., and Kehrer, J.P. Differential toxicities of cyclophosphamide and its glutathione metabolites to A549 cells. Toxicol. in Vitro. 9:21-26

1994

Gargas, M., R. Norton, M. Harris, D. Paustenbach, and B. Finley. 1994. Urinary excretion of chromium following ingestion of chromite ore processing residue in humans: implications for biomonitoring. Risk Anal. 14(6):1019-1024.

Haws, L.C., B.A. Jackson, D. Turnbull, and W.E. Dressler. 1994. Two approaches for assessing human cancer risk from disperse blue 1. Reg Toxicol Pharmacol. 19:80-96.

1993

Copeland, T.L., D.J. Paustenbach, M.A. Harris, and J. Otani. 1993. Comparing the results of a Monte Carlo analysis with EPA's reasonable maximum exposed individual (RMEI): a case study of a former wood treatment site. Reg Toxicol Pharmacol. 18:275-312.

Harris, M., T. Zacharewski, and S. Safe. 1993. Comparative potencies of Aroclors 1232, 1248, 1254, and 1260 in male wistar rats—Assessment of the toxic equivalency factor (TEF) approach for polychlorinated biphenyls (PCBs). Fund Appl Toxicol. 20:456-463.

1992

Wenning, R.J., M.A. Harris, M.J. Ungs, D.J. Paustenbach, and H. Bedbury. 1992. Chemometric comparison of polychlorinated dibenzo-p-dioxin and dibenzofuran residues in surficial sediments from Newark Bay, New Jersey and other industrialized waterways. Arch Environ Contam Toxicol. 22:397-413.

Wenning, R.J., M.A. Harris, D.J. Paustenbach, and H. Bedbury. 1992. Potential sources of 1,2,8,9-tetrachlorodibenzo-p-dioxin in the aquatic environment. Ecotoxicol Environ Safety. 23(2):133-146.

Zacharewski, T., M. Harris, L. Biegel, V. Morrison, M. Merchant, and S. Safe. 1992. 6-Methyl-1,3,8-trichlorodibenzofuran (MCDF) as an antiestrogen in human and rodent cancer cell lines: evidence for the role of the Ah receptor. Toxicol Appl Pharmacol. 113:311-318.

1991

Couture-Haws, L., M.W. Harris, A.C. Lockhart, and L.S. Birnbaum. 1991. Evaluation of the persistence of hydronephrosis induced in mice following in uteri and/or lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Toxicol Appl Pharmacol. 107:402-412.

Couture-Haws, L., M.W. Harris, M.M. McDonald, A.C. Lockhart, and L.S. Birnbaum. 1991. Hydronephrosis in mice exposed to TCDD-contaminated breast milk: identification of the peak period of sensitivity and assessment of potential recovery. Toxicol Appl Pharmacol. 107:413-428.

Frankos, V.H., D.F. Schmitt, L.C. Haws, A.J. McEvily, R. Iyengar, S.A. Miller, I.C. Munro, F.M. Clydsdale, A.L. Forbes, and R.M. Sauer. 1991. Generally recognized as safe (GRAS) evaluation of 4-hexylresorcinol for use as a processing aid for the prevention of melanosis in shrimp. Reg Toxicol Pharmacol. 14:202-212.

Piskorska-Pliszczynska, J., B. Astroff, T. Zacharewski, M. Harris, R. Rosengren, V. Morrison, L. Safe, and S. Safe. 1991. Mechanism of action of 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonists: characterization of 6-[125I]methyl-8-iodo-1,3-dichlorodibenzofuran-Ah receptor complexes. Arch Biochem Biophy. 284(1):193-200.

Safe, S., B. Astroff, M. Harris, T. Zacharewski, R. Dickerson, M. Romkes, and L. Biegel. 1991. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related compounds as antioestrogens: characterization and mechanism of action. Pharmacol Toxicol. 69:400-409.

Safe, S., M. Harris, L. Biegel, and T. Zacharewski. 1991. Mechanism of Action of TCDD as an antiestrogen in transformed human breast cancer and rodent cell lines. Banbury Report 35: Biological Basis for Risk Assessment of Dioxins and Related Compounds Cold Spring Harbor Laboratory Press. 367-377.

Zacharewski, T., M. Harris, and S. Safe. 1991. Evidence for a possible mechanism of action of the 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated decrease of nuclear estrogen receptor levels in wild-type and mutant Hepa 1c1c7 cells. Biochem Pharmacol. 41:1931-1939.

1990

Couture-Haws, L., B.D. Abbott, and L.S. Birnbaum. 1990. A critical review of the developmental toxicity and teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin: recent advances in understanding the mechanism. Teratol. 42:619-627.

Couture, L.A., M.W. Harris, and L.S. Birnbaum. 1990. Characterization of the peak period of sensitivity for the induction of hydronephrosis in C57BL/6N mice following exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Fundam Appl Toxicol. 15:142-150.

Harris, M., J. Piskorska-Pliszczynska, T. Zacharewski, and S. Safe. 1990. Human breast cancer cell lines as models for investigating the effects of TCDD and related compounds. Chemosphere. 20(7-9):1135-1140.

Harris, M., T. Zacharewski, J. Piskorska-Pliszcyznska, R. Rosengren, and S. Safe. 1990. Structure-dependent induction of aryl hydrocarbon hydroxylase activity in C57BL/6 Mice by 2,3,7,8-tetrachlordibenzo-p-dioxin and related congeners: mechanistic studies. Toxicol Appl Pharmacol. 105:243-253.

Harris, M., T. Zacharewski, and S. Safe. 1990. Effects of 2,3,7,8-tetrachorodibenzo-p-dioxin and related compounds on the occupied nuclear estrogen receptor in MCF-7 human breast cancer cells. Cancer Res. 50:3579-3584.

Randerath, K., K.L. Putman, E. Randerath, M. Harris, T. Zacharewski, and S. Safe. 1990. Effects of 2,3,7,8-TCDD and related compounds on the levels of age-dependent I-spot DNA adducts in the liver of female and male Sprague-Dawley rats. Chemosphere. 20(7-9):1049-1052.

Randerath, K., K.L. Putman, E. Randerath, T. Zacharewski, M. Harris, and S. Safe. 1990. Effects on 2,3,7,8-tetrachlorodibenzo-p-dioxin on I-compounds in hepatic DNA of Sprague-Dawley rats: sex specific effects and structure-activity relationships. Toxicol Appl Pharmacol. 103:271-280.

Safe, S., M. Harris, T. Zacharewski, and L. Biegel. 1990. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) as an antiestrogen in human breast cancer cells: mechanistic studies. Proceedings Dioxin `90, Eco-Informa Press. Bayreuth, Germany, 1:137-140.

1989

Biegel, L., M. Harris, D. Davis, R. Rosengren, L. Safe, and S. Safe. 1989. 2,2',4,4',5,5'-hexachlorobiphenyl as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist in C57BL/6J mice. Toxicol Appl Pharmacol. 97:561-571.

Birnbaum, L.S., L.A. Couture, and M.R. Elwell. 1989. Subchronic effects of exposure to Octachlorodibenzo-p-dioxin (OCDD). Chemosphere. 18(1-6):389-390.

Couture, L.A., M.W. Harris, and L.S. Birnbaum. 1989. Developmental toxicity of 2,3,4,7,8-pentachlorodibenzofuran (4-PeCDF) in the Fischer 344 rat. Fundam Appl Toxicol. 12:358-366.

Harris, M., J. Piskorska-Pliszczynska, T. Zacharewski, M. Romkes, and S. Safe. 1989. Structure-dependent induction of aryl hydrocarbon hydroxylase in human breast cancer cell lines and characterization of the Ah receptor. Cancer Res. 49:4531-4535.

Harris, M., T. Zacharewski, B. Astroff, C. Kamps, and S. Safe. 1989. Characterization of 6-methyl-1,3,8-trichlorodibenzofuran (MCDF) as a 2,3,7,8-TCDD antagonist in male rats: induction of monooxygenases. Chemosphere. 19:769-772.

Harris, M., T. Zacharewski, B. Astroff, and S. Safe. 1989. Partial antagonism of 2,3,7,8-tetrachlorodibenzo-p-dioxin mediated induction of aryl hydrocarbon hydroxylase by 6-methyl-1,3,8-trichlorodibenzofuran: mechanistic studies. Mol Pharmacol. 35:729-735.

Safe, S., G. Mason, T. Sawyer, T. Zacharewski, M. Harris, C. Yao, B. Keys, K. Farrell, M. Holcomb, D. Davis, L. Safe, J. Piskorska-Pliszcyzynska, B. Leece, M. Denomme, O. Hutzinger, H. Thoma, B. Chittim, and J. Madge. 1989. Development and validation of in vitro induction assays for toxic halogenated aromatic mixtures: a review. Toxicol Ind Health. 5(5):757-775.

Safe, S., T. Zacharewski, L. Safe, M. Harris, C. Yao, and M. Holcomb. 1989. Validation of the AHH induction bioassay for the determination of 2,3,7,8-TCDD toxic equivalents. Chemosphere. 18(1-6):941-946.

Zacharewski, T., M. Harris, and S. Safe. 1989. Induction of cytochrome P450-dependent monooxygenase activities in rat hepatoma H-4-IIE cells in culture by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds: mechanistic studies using radiolabeled congeners. Arch Biochem Biophys. 272(2):344-355.

Zacharewski, T., M. Harris, S. Safe, H. Thoma, G. Hauschulz, E. Knorr, and O. Hutzinger. 1989. Application of the in vitro AHH induction bioassay for determining 2,3,7,8-TCDD equivalents: pyrolyzed flame retardant mixtures. Chemosphere. 18(1-6):383-387.

1988

Birnbaum, L.S. and L.A. Couture. 1988. Disposition of Octachlorodibenzo-p-dioxin (OCDD) in male rats. Toxicol Appl Pharmacol. 93:22-30.

Couture, L.A., M.R. Elwell, and L.S. Birnbaum. 1988. Dioxin-like effects observed in male rats following exposure to Octachlorodibenzo-p-dioxin (OCDD) during a 13-week study. Toxicol Appl Pharmacol. 93:31-46.

Harris, M., C. Kamps, and S. Safe. 1988. Role of the 4-5S binding protein in the induction of aryl hydrocarbon hydroxylase in the rat. Carcinogenesis. 9(8):1475-1479.

Zacharewski, T., M. Harris, S. Safe, H. Thoma, and O. Hutzinger. 1988. Applications of the in vitro aryl hydrocarbon hydroxylase induction assay for determining “2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents”: pyrolyzed brominated flame retardants. Toxicology. 51:177-189.