PUBLICATIONS & PRESENTATIONS

Manuscripts

Thompson, C.M., Sonawane, B., and Grafström, R.C. The Ontogeny, Distribution and Regulation of Alcohol Dehydrogenase 3: Implications for Pulmonary Physiology. Drug Metabolism and Disposition (in press).

Urban, J.D., J.A. Tachovsky, D.F. Staskal, L.C. Haws, and M.A. Harris. 2009. Assessment of Human Health Risks Posed by Consumption of Fish from the Lower Passaic River, New Jersey. Sci Total Environ. in press: doi:10.1016/j.scitotenv.2009.03.004

L.L.F. Scott, Staskal, D.F., Williams ES, Luksemburg WJ, Urban JD, Nguyen LM, Haws LC, Birnbaum LS, Paustenbach DJ, Harris MA. 2009. Levels of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls in southern Mississippi catfish and estimation of potential health risks. Chemosphere. 74(7): 1002-10.

2008

Staskal, D.F., L.L.F. Scott, L.C. Haws, W.J. Luksemburg, L.S. Birnbaum, L.M. Nguyen, J.U. Urban, E.S. Williams, D.J. Paustenbach, and M.A. Harris. 2008. Assessment of Polybrominated diphenyl ether Exposures and Health Risks Associated with Consumption of Southern Mississippi Catfish. Environ Sci Technol.. 42(17): 6755-61.

Donovan, E., K. Unice, J.D. Roberts, M. Harris, and B. Finley. 2008. Risk of Gastrointestinal Disease Associated with Exposure to Pathogens in the Water of the Lower Passaic River. Appl Environ Microbiol. 74:994-1003.

Donovan, E.P., D.F. Staskal, K.M. Unice, J.D. Roberts, L.C. Haws, B.L. Finley, and M.A. Harris. 2008. Risk of Gastrointestinal Disease Associated with Exposure to Pathogens in the Sediments of the Lower Passaic River. Appl Environ Microbiol. 74:1004-1018.

Haws, L.C., J.A. Tachovsky, E.S Williams, L.F. Scott, D. Paustenbach, and M. Harris. 2008. Assessment of Potential Human Health Risks Posed by Benzene in Beverages, J. Food Sci. 73(4), T33-41.

Richardson, V.M., D.F. Staskal, D.G. Ross, J.J. Diliberto, M.J. Devito, and L.S. Birnbaum. 2008. Possible mechanisms of thyroid hormone disruption in mice by BDE 47, a major polybrominated diphenyl ether congener. Toxicol Appl Pharmacol. 226(3):244-50.

Scott, L.L.F., M. Harris, K.M. Unice, P. Scott, L.M. Nguyen, L.C. Haws, and D. Paustenbach. 2008. Addendum to: Evaluation of PCDD/F and dioxin-like PCB serum concentration data from the 2001-2002 National Health and Nutrition Examination Survey of the United States population. J Exp Sci Env Epidemiol. 1-9.

 

2007

Ferriby, L.L., J.S. Knutsen, M. Harris, K.M. Unice, P. Scott, P. Nony, L.C. Haws, and D. Paustenbach. 2007. Evaluation of PCDD/F and dioxin-like PCB serum concentration data from the 2001-2002 National Health and Nutrition Examination Survey of the United States Population. J Exp Anal Env Epidemiol. 17: 358-371.

Reedy, R. C., B. R. Scanlon, J. P. Nicot, and J. A. Tachovsky. 2007. Unsaturated Zone Arsenic Distribution and Implications for Groundwater Contamination. Environ Sci Technol., vol 41(20) pp. 6914-6919.

Scanlon, B. R., R. C. Reedy, and J. A. Tachovsky. 2007. Semiarid unsaturated zone chloride profiles: Archives of past land use change impacts on water resources in the southern High Plains, United States. Water Res Res., vol. 43 doi: 10.1029/2006-WR005769.

Urban, J.D., W.P. Clarke, M. von Zastrow, B. Kobilka, D.E. Nichols, H. Weinstein, J.A. Javitch, B.L. Roth, A. Christopoulos, P.M. Sexton, K.J. Miller, M. Spedding, and R.B. Mailman. 2007. Functional selectivity and classical concepts of quantitative pharmacology. J. Pharmacol Exp Therap. 320 (1): 1-13.

Urban, J.D., G. Vargas, M. von Zastrow, and R.B. Mailman. 2007. Aripiprazole has functionally selective actions at D2 receptor-mediated signaling pathways. Neuropsychopharmacology. 32 (1): 67-77.

2006

Haws, L.C., S. Su, M. Harris, M. DeVito, N. Walker, W. Farland, B. Finley, and L. Birnbaum. 2006. Development of a refined database of mammalian relative potency estimates for dioxin-like compounds. Toxicol Sci. 89(1):4-30.

Paustenbach, D.J., K. Fehling, P. Scott, M. Harris, and B. Kerger. 2006. Identifying a soil clean-up criteria for dioxin in urban residential soils: How have 20 years of research and risk assessment experience affected the analysis? J Toxicol Environ Health, Part B. 9:87-145.

Staskal, D.F., J.J. Diliberto and L.S. Birnbaum. 2006. Impact of repeated exposure on the toxicokinetics of BDE 47 in mice. Toxicol Sci. 89:380-5.

Staskal, D.F., J.J. Diliberto, and L.S. Birnbam. 2006. Disposition of BDE 47 in developing mice. Toxicol Sci. 90:309-16.

Staskal, D.F., H. Hakk, D. Bauer, J.J. Diliberto, and L.S. Birnbam. 2006. Toxicokinetics of Polybrominated diphenyl ether congeners 47, 99, 100, and 153 in mice. Toxicol Sci. 94:28-37.

Van den Berg, M., L. Birnbaum, M. Denison, M. De Vito, W. Farland, M. Feeley, H. Fiedler, H. Hakansson, A. Hanberg, L.C. Haws, M. Rose, S. Safe, D. Schrenk, C. Tohyama, A. Tritscher, J. Tuomisto, M. Tysklind, N. Walker, and R.E. Peterson. 2006. The 2005 World Health Organization Reevaluation of Human and Mammalian Toxic Equivalency Factors for Dioxins and Dioxin-Like Compounds. Toxicol Sci. 93(2):223-241.

2005

Staskal, D.F., J.J. Diliberto, M.J. DeVito and L.S. Birnbaum. 2005. Inhibition of Human and Rat CYP1A2 by TCDD and Dioxin-like Chemicals. Toxicol Sci. 84: 225-31.

Staskal, D.F., J.J. Diliberto, M.J. DeVito, and L.S. Birnbaum. 2005. Toxicokinetics of BDE 47 in Female Mice: Effects of Dose, Route of Exposure, and Time. Toxicol Sci. 83: 215-23.

2004

Birnbaum, L.S., and D.F. Staskal. 2004. Brominated Flame Retardants: Cause for Concern? Environ Health Perspect. 112: 9-17.

Gay, E.A., J.D. Urban, D.E. Nichols, G.S. Oxford, and R.B. Mailman. 2004. Functional selectivity of D2 receptor ligands in a Chinese hamster ovary hD2L cell line: evidence for induction of ligand-specific receptor states. Mol Pharmacol. 66 (1): 97 - 105.

Schecter, A., O. Papke, K.C. Tung, D.F. Staskal, and L. Birnbaum. 2004. Polybrominated diphenyl ether contamination of United States food. Environ Sci Technol. 38(20): 5306-11.

2003

Birnbaum, L.S., D.F. Staskal, and J.J. Diliberto. 2003. Health effects of polybrominated dibenzo-p-dioxins (PBDDs) and dibenzofurans (PBDFs). Environ Inter. 29: 855-860.

Proctor, D., J. Panko, E. Liebig, K. Mundt, M. Buczynski, R. Barnhart, M. Harris, R. Morgan, B. Finley, and D. Paustenbach. 2003. Workplace concentrations of airborne hexavalent chromium for the Painesville, Ohio chromate production plant. Appl Occ Environ Hyg J. 18(6):430-449.

2002

Grant, R.L., R. Rodriguez, C.S. Hofelt, and L.C. Haws. 2002. Shortcomings in USEPA's approach for predicting risk due to consumption of animal food products impacted by air emissions from hazardous waste combustion facilities: a case study involving phthalates. Human Ecol Risk Assess. 8(5):1137-1154.

Scott, P., J. Petura, and M. Harris. 2002. Derivation of a liquid to solid ratio for ASTM method D3987 85 for soils containing chromite ore processing residue using selected unsaturated zone models. Soil Sed Contam. 12(4):443-480.

2001

Hofelt, C.S., M. Honeycutt, J.T. McCoy, and L.C. Haws. 2001. Development of a metabolism factor for polycyclic aromatic hydrocarbons for use in multipathway risk assessments for hazardous waste combustion facilities. Reg Toxicol Pharmacol. 33:60-65.

2000

Finley, B.L., D.M. Proctor, M. Harris, and J.F. Fowler. 2000. Letter to the editor. American J Contact Derm. 123-125.

1997

Costa, M., A. Zhitkovich, M. Harris, D. Paustenbach, and M. Gargas. 1997. DNA-Protein crosslinks produced by various chemicals in cultured human lymphocytes. J Toxicol Environ Health.

Scott, P., B. Finley, M. Harris, and D. Rabbe. 1997. Determination of background airborne hexavalent chromium concentrations in industrial areas. J Air Waste Manage. Assoc. 47:592-600.

1994

Gargas, M., R. Norton, M. Harris, D. Paustenbach, and B. Finley. 1994. Urinary excretion of chromium following ingestion of chromite ore processing residue in humans: implications for biomonitoring. Risk Anal. 14(6):1019-1024.

Haws, L.C., B.A. Jackson, D. Turnbull, and W.E. Dressler. 1994. Two approaches for assessing human cancer risk from disperse blue 1. Reg Toxicol Pharmacol. 19:80-96.

1993

Copeland, T.L., D.J. Paustenbach, M.A. Harris, and J. Otani. 1993. Comparing the results of a Monte Carlo analysis with EPA's reasonable maximum exposed individual (RMEI): a case study of a former wood treatment site. Reg Toxicol Pharmacol. 18:275-312.

Harris, M., T. Zacharewski, and S. Safe. 1993. Comparative potencies of Aroclors 1232, 1248, 1254, and 1260 in male wistar rats—Assessment of the toxic equivalency factor (TEF) approach for polychlorinated biphenyls (PCBs). Fund Appl Toxicol. 20:456-463.

1992

Wenning, R.J., M.A. Harris, M.J. Ungs, D.J. Paustenbach, and H. Bedbury. 1992. Chemometric comparison of polychlorinated dibenzo-p-dioxin and dibenzofuran residues in surficial sediments from Newark Bay, New Jersey and other industrialized waterways. Arch Environ Contam Toxicol. 22:397-413.

Wenning, R.J., M.A. Harris, D.J. Paustenbach, and H. Bedbury. 1992. Potential sources of 1,2,8,9-tetrachlorodibenzo-p-dioxin in the aquatic environment. Ecotoxicol Environ Safety. 23(2):133-146.

Zacharewski, T., M. Harris, L. Biegel, V. Morrison, M. Merchant, and S. Safe. 1992. 6-Methyl-1,3,8-trichlorodibenzofuran (MCDF) as an antiestrogen in human and rodent cancer cell lines: evidence for the role of the Ah receptor. Toxicol Appl Pharmacol. 113:311-318.

1991

Couture-Haws, L., M.W. Harris, A.C. Lockhart, and L.S. Birnbaum. 1991. Evaluation of the persistence of hydronephrosis induced in mice following in uteri and/or lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Toxicol Appl Pharmacol. 107:402-412.

Couture-Haws, L., M.W. Harris, M.M. McDonald, A.C. Lockhart, and L.S. Birnbaum. 1991. Hydronephrosis in mice exposed to TCDD-contaminated breast milk: identification of the peak period of sensitivity and assessment of potential recovery. Toxicol Appl Pharmacol. 107:413-428.

Frankos, V.H., D.F. Schmitt, L.C. Haws, A.J. McEvily, R. Iyengar, S.A. Miller, I.C. Munro, F.M. Clydsdale, A.L. Forbes, and R.M. Sauer. 1991. Generally recognized as safe (GRAS) evaluation of 4-hexylresorcinol for use as a processing aid for the prevention of melanosis in shrimp. Reg Toxicol Pharmacol. 14:202-212.

Piskorska-Pliszczynska, J., B. Astroff, T. Zacharewski, M. Harris, R. Rosengren, V. Morrison, L. Safe, and S. Safe. 1991. Mechanism of action of 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonists: characterization of 6-[125I]methyl-8-iodo-1,3-dichlorodibenzofuran-Ah receptor complexes. Arch Biochem Biophy. 284(1):193-200.

Safe, S., B. Astroff, M. Harris, T. Zacharewski, R. Dickerson, M. Romkes, and L. Biegel. 1991. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related compounds as antioestrogens: characterization and mechanism of action. Pharmacol Toxicol. 69:400-409.

Safe, S., M. Harris, L. Biegel, and T. Zacharewski. 1991. Mechanism of Action of TCDD as an antiestrogen in transformed human breast cancer and rodent cell lines. Banbury Report 35: Biological Basis for Risk Assessment of Dioxins and Related Compounds Cold Spring Harbor Laboratory Press. 367-377.

Zacharewski, T., M. Harris, and S. Safe. 1991. Evidence for a possible mechanism of action of the 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated decrease of nuclear estrogen receptor levels in wild-type and mutant Hepa 1c1c7 cells. Biochem Pharmacol. 41:1931-1939.

1990

Couture-Haws, L., B.D. Abbott, and L.S. Birnbaum. 1990. A critical review of the developmental toxicity and teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin: recent advances in understanding the mechanism. Teratol. 42:619-627.

Couture, L.A., M.W. Harris, and L.S. Birnbaum. 1990. Characterization of the peak period of sensitivity for the induction of hydronephrosis in C57BL/6N mice following exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Fundam Appl Toxicol. 15:142-150.

Harris, M., J. Piskorska-Pliszczynska, T. Zacharewski, and S. Safe. 1990. Human breast cancer cell lines as models for investigating the effects of TCDD and related compounds. Chemosphere. 20(7-9):1135-1140.

Harris, M., T. Zacharewski, J. Piskorska-Pliszcyznska, R. Rosengren, and S. Safe. 1990. Structure-dependent induction of aryl hydrocarbon hydroxylase activity in C57BL/6 Mice by 2,3,7,8-tetrachlordibenzo-p-dioxin and related congeners: mechanistic studies. Toxicol Appl Pharmacol. 105:243-253.

Harris, M., T. Zacharewski, and S. Safe. 1990. Effects of 2,3,7,8-tetrachorodibenzo-p-dioxin and related compounds on the occupied nuclear estrogen receptor in MCF-7 human breast cancer cells. Cancer Res. 50:3579-3584.

Randerath, K., K.L. Putman, E. Randerath, M. Harris, T. Zacharewski, and S. Safe. 1990. Effects of 2,3,7,8-TCDD and related compounds on the levels of age-dependent I-spot DNA adducts in the liver of female and male Sprague-Dawley rats. Chemosphere. 20(7-9):1049-1052.

Randerath, K., K.L. Putman, E. Randerath, T. Zacharewski, M. Harris, and S. Safe. 1990. Effects on 2,3,7,8-tetrachlorodibenzo-p-dioxin on I-compounds in hepatic DNA of Sprague-Dawley rats: sex specific effects and structure-activity relationships. Toxicol Appl Pharmacol. 103:271-280.

Safe, S., M. Harris, T. Zacharewski, and L. Biegel. 1990. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) as an antiestrogen in human breast cancer cells: mechanistic studies. Proceedings Dioxin `90, Eco-Informa Press. Bayreuth, Germany, 1:137-140.

1989

Biegel, L., M. Harris, D. Davis, R. Rosengren, L. Safe, and S. Safe. 1989. 2,2',4,4',5,5'-hexachlorobiphenyl as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist in C57BL/6J mice. Toxicol Appl Pharmacol. 97:561-571.

Birnbaum, L.S., L.A. Couture, and M.R. Elwell. 1989. Subchronic effects of exposure to Octachlorodibenzo-p-dioxin (OCDD). Chemosphere. 18(1-6):389-390.

Couture, L.A., M.W. Harris, and L.S. Birnbaum. 1989. Developmental toxicity of 2,3,4,7,8-pentachlorodibenzofuran (4-PeCDF) in the Fischer 344 rat. Fundam Appl Toxicol. 12:358-366.

Harris, M., J. Piskorska-Pliszczynska, T. Zacharewski, M. Romkes, and S. Safe. 1989. Structure-dependent induction of aryl hydrocarbon hydroxylase in human breast cancer cell lines and characterization of the Ah receptor. Cancer Res. 49:4531-4535.

Harris, M., T. Zacharewski, B. Astroff, C. Kamps, and S. Safe. 1989. Characterization of 6-methyl-1,3,8-trichlorodibenzofuran (MCDF) as a 2,3,7,8-TCDD antagonist in male rats: induction of monooxygenases. Chemosphere. 19:769-772.

Harris, M., T. Zacharewski, B. Astroff, and S. Safe. 1989. Partial antagonism of 2,3,7,8-tetrachlorodibenzo-p-dioxin mediated induction of aryl hydrocarbon hydroxylase by 6-methyl-1,3,8-trichlorodibenzofuran: mechanistic studies. Mol Pharmacol. 35:729-735.

Safe, S., G. Mason, T. Sawyer, T. Zacharewski, M. Harris, C. Yao, B. Keys, K. Farrell, M. Holcomb, D. Davis, L. Safe, J. Piskorska-Pliszcyzynska, B. Leece, M. Denomme, O. Hutzinger, H. Thoma, B. Chittim, and J. Madge. 1989. Development and validation of in vitro induction assays for toxic halogenated aromatic mixtures: a review. Toxicol Ind Health. 5(5):757-775.

Safe, S., T. Zacharewski, L. Safe, M. Harris, C. Yao, and M. Holcomb. 1989. Validation of the AHH induction bioassay for the determination of 2,3,7,8-TCDD toxic equivalents. Chemosphere. 18(1-6):941-946.

Zacharewski, T., M. Harris, and S. Safe. 1989. Induction of cytochrome P450-dependent monooxygenase activities in rat hepatoma H-4-IIE cells in culture by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds: mechanistic studies using radiolabeled congeners. Arch Biochem Biophys. 272(2):344-355.

Zacharewski, T., M. Harris, S. Safe, H. Thoma, G. Hauschulz, E. Knorr, and O. Hutzinger. 1989. Application of the in vitro AHH induction bioassay for determining 2,3,7,8-TCDD equivalents: pyrolyzed flame retardant mixtures. Chemosphere. 18(1-6):383-387.

1988

Birnbaum, L.S. and L.A. Couture. 1988. Disposition of Octachlorodibenzo-p-dioxin (OCDD) in male rats. Toxicol Appl Pharmacol. 93:22-30.

Couture, L.A., M.R. Elwell, and L.S. Birnbaum. 1988. Dioxin-like effects observed in male rats following exposure to Octachlorodibenzo-p-dioxin (OCDD) during a 13-week study. Toxicol Appl Pharmacol. 93:31-46.

Harris, M., C. Kamps, and S. Safe. 1988. Role of the 4-5S binding protein in the induction of aryl hydrocarbon hydroxylase in the rat. Carcinogenesis. 9(8):1475-1479.

Zacharewski, T., M. Harris, S. Safe, H. Thoma, and O. Hutzinger. 1988. Applications of the in vitro aryl hydrocarbon hydroxylase induction assay for determining “2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents”: pyrolyzed brominated flame retardants. Toxicology. 51:177-189.