2017

Wikoff DS, Rager J, Harvey S, Haws L, Chappell G, Borghoff S. 2017. Framework for quantitative consideration of study quality and relevance in the systematic evaluation of mechanistic data per the Ten Key Characteristics of Carcinogens. Poster presented at Society of Toxicology Annual Meeting, March 15, Baltimore, MD.

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Doepker D, Tyndall K, Lane R, Wikoff D, Thompson C, Harvey S, Schmitt D. 2017. A proposed ADI for nitrate. Poster presented at Society of Toxicology Annual Meeting, March 16, Baltimore, MD.

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Borghoff SJ, Ring C, Banton MI, Leavens TL. 2017. Ethyl tertiary butyl ether (ETBE) and tertiary butyl alcohol (TBA) physiologically based pharmacokinetic (PBPK) model in rats: Contribution of binding to 𝜶2u-globulin and non-linear kinetics to kidney and liver responses in rats. Poster presented at Society of Toxicology Annual Meeting, March 16, Baltimore, MD.

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Thompson C, Rager J, Suh M, Proctor D, Haws L, Harris M. 2017. Mechanistic support for nonlinear risk assessment of rat oral cavity tumors induced by exposure to Cr(VI) in drinking water. Poster presented at Society of Toxicology Annual Meeting. March 15, Baltimore, MD.

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Chappell G, Welsh B, Harvey S, Harris M, Wikoff D. 2017. Validation and application of a text mining tool in the identification and categorization of mechanistic data: A case study in improving problem formulation of carcinogenicity assessments. Poster presented at Society of Toxicology Annual Meeting, March 15, Baltimore, MD.

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Proctor DM, Suh M, Dunsmore D, Verwiel A, Casteel S. 2017. Bioaccessibility and relative oral bioavailability of cobalt and nickel from metal alloys in soil and dust. Poster presented at Society of Toxicology Annual Meeting, March 15, Baltimore, MD.

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Kirman CR, Proctor D, Suh M, Haws L, Harris M, Thompson C, Hays S. 2017. Using physiologically based pharmacokinetic modeling to address potentially sensitive subpopulations exposed to hexavalent chromium. Poster presented at Society of Toxicology Annual Meeting, March 15, Baltimore, MD.

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Rager JE, Thompson CM, Ring C, Fry RC, Harris MA. 2017. Integration of transcriptomics and high-throughput screening predictions with robust in vivo data to inform hexavalent chromium mode of action. Poster presented at Society of Toxicology Annual Meeting, March 14, Baltimore, MD.

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Thompson C, Kirman C, Suh M, Proctor D, Haws L, Harris M, Hays S. 2017. Risk assessment of oral exposure to Cr(VI): Integration of mode of action, pharmacokinetics, and dose-response modeling. Poster presented at Society of Toxicology Annual Meeting, March 14, Baltimore, MD.

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Mease K, Kimzey A, Lansita J. 2017. Failed dose formulation analysis during a GLP study — Now what? Poster presented at Society of Toxicology Annual Meeting, March 14, Baltimore, MD.

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Suh M, Harvey S, Wikoff D, Mittal L, Ring C, Goodmanson A, Proctor D. 2017. Meta-analysis of hexavalent chromium and stomach cancer. Poster presented at Society of Toxicology Annual Meeting, March 13, Baltimore, MD.

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Rager J, Isaacs K, Biryol D, Newton S, Strynar M, Sobus J. 2017. Innovative screening methods to identify chemical exposure signatures and linkages to toxicity: Case study with house dust. Presented at Society of Toxicology Annual Meeting, March 13, Baltimore, MD.

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2016

Bichteler A. 2016. Constrained multiple imputation: A case study in estimation and modeling on data missing below the limit of detection. Presented in the “Melding Dose-Response Relationships” session at the Society of Risk Analysis, December 14, San Diego, CA.

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Rager J. 2016. Integration of high-content and high-throughput screening data to inform hexavalent chromium mode of action. Environmental Mutagenesis and Genomics Society, September 26, Kansas City, KS. 

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Rager J, Thompson C, Auerbach S, Fry R. 2016. Integrating genomic and epigenomic data into risk assessment applications through dose response modeling: Case study with prenatal arsenic exposure. Environmental Mutagenesis and Genomics Society, September 25, Kansas City, KS. 

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Haws L. 2016. Vapor intrusion – Solid ground or quick sand? Invited Speaker. Presented at the 28th Annual Texas Environmental Superconference, August 5, Austin, TX.

Haws L. 2016. Vapor intrusion – Technical issues. Invited Speaker. Presented at the Semi-Annual South Central Regional Meeting of the Auditing Roundtable, August 3, Austin, TX.

Borghoff SJ. 2016. Organization and review of mechanistic data according to “Ten Key Characteristics of Carcinogens” (TKCC) {Smith et al., 2016}. Presented at the 42nd Annual Summer Meeting of the Toxicology Forum, July, Salt Lake City, UT.

Haws L. 2016. Trichlorethylene exposure and development of fetal cardiac malformations: What do the data tell us about inhalation exposures resulting from vapor intrusion and potential health risks to pregnant women? – Introduction. Presented at the Society of Toxicology’s 55th Annual Meeting, March 13-17, New Orleans, LA.

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Proctor DM. 2016. Cancer risk assessment for ingested hexavalent chromium:  Challenges and controversies – Introduction. Presented at the Society of Toxicology’s 55th Annual Meeting, March 13-17, New Orleans, LA [session introduction; no abstract].

Wikoff D, Borghoff SJ, Rager JE, Haws LC. 2016. Human relevance assessment of tetrabromobisphenol-A (TBBPA) induced uterine adenocarcinomas: Mode of action dependent on high dose molecular initiating event (MIE). Presented in the “Flame Retardants” session at the Society of Toxicology’s 55th Annual Meeting, March 13-17, New Orleans, LA.

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Suh M. 2016. Cumulative risk assessment of urban air toxics: A pilot study in San Antonio, Texas. Presented in the “Quantitative Cumulative Risk Assessment: Is it Feasible Today?” Session of the Society of Toxicology’s 55th Annual Meeting, March 13-17, New Orleans, LA.

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Thompson CM. 2016. Non-mutagenic MOA for Cr(VI) involving intestinal cytotoxicity and regenerative hyperplasia. Platform presentation in the “The Cancer Risk Assessment for Ingested Hexavalent Chromium: Challenges and Controversies” Session. Presented at the Society of Toxicology’s 55th Annual Meeting, March 13-17, New Orleans, LA.

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Rager JE,  Strynar MJ, Liang S, McMahen R, Richard AM, Grulke CM, Wambaugh JF, Isaacs KK, Judson R, Williams AJ, Sobus JR. 2016. Linking high resolution mass spectrometry data with exposure and toxicity forecasts to advance high-throughput environmental monitoring. Presented at the Society of Toxicology’s 55th Annual Meeting, March 13-17, New Orleans, LA.

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Borghoff SJ,  Wikoff D, Rager JE, Haws LC. 2016. Tetrabromobisphenol A (TBBPA); Dose- and time-dependent changes in plasma TBBPA and its conjugates over 28 days of administration. Presented at the Society of Toxicology’s 55th Annual Meeting, March 13-17, 2016. New Orleans, LA.

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DeVito MJ, Borghoff SJ, Zorilla LM, Shockley K, Kissling G,  Travlos G. 2016. The effects of a high fat (HF) diet on male diversity outbred (DO) mice. Presented at the Society of Toxicology’s 55th Annual Meeting, March 13-17, New Orleans, LA.

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Cullen JM, Ward JM, Thompson CM. 2016. Re-evaluation and classification of duodenal lesions in B6C3F1 mice and F344 rats from four studies of hexavalent chromium in drinking water. Presented at the Society of Toxicology’s 55th Annual Meeting, March 13-17, New Orleans, LA.

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Thompson CM, Suh M, Proctor DM, Rager JE, Haws LC, and Harris MA. 2016. Assessment of the in vivo genotoxicity of CrVI in target organs identified in a two-year cancer bioassay. Presented at the Society of Toxicology’s 55th Annual Meeting, March 13-17, New Orleans, LA.

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Suh M, Crump K, Mittal L, Hirsch S, Valdes Salgado R, BartlettC, Van Landingham C, Rohr A, Proctor DM. 2016. Inhalation cancer risk assessment of hexavalent chromium based on updated mortality for Painesville chromate production workers. Presented at the Society of Toxicology’s 55th Annual Meeting, March 13-17, New Orleans, LA.

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Brorby GP, Suh M, Thompson CM, Mittal L, Proctor DM. 2016. Inhalation cancer risk assessment of cobalt metal. Presented at the Society of Toxicology’s 55th Annual Meeting, March 13-17, New Orleans, LA.

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Verwiel A, Proctor D, Tachovsky A. 2016. Principal component analysis of metals in soil and dust to distinguish background and anthropogenic sources in an urban area. Association for Environmental Health and Sciences Foundation Annual Meeting, March 14, San Diego, CA.

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2015

Hughes BJ, LeBaron MJ, Thomas J, Kan HL, Lynch AM, Borghoff SJ, Green S, Mensing T, Sarang SS, Smulders CJGM. 2015. Activation of CAR and PXR nuclear receptors in the liver of MIBK-exposed mice. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, 2015. San Diego, CA.

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Kirman CR, Proctor DM, Suh M, Hays S. 2015. Reduction of hexavalent chromium by gastric fluids from fed and fasted individuals with applications to toxicokinetic modeling. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

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Suh M, Mittal L, Hirsch S, Valdes R, Bartlett C, Rohr A, Proctor D. 2015. Lung cancer risk in chromate production workers exposed to hexavalent chromium. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

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Britt J, James R. 2015. Welding and occupational exposure to manganese fumes and Parkinson’s disease:  An evidence-based causation analysis. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

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Mounho-Zamora B, Weissman I, Volkmer J, Willingham S, Prohaska S, Howard M, Jie L, Majeti R.2015.  Nonclinical safety assessment of a monoclonal antibody against CD47. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

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Doepker C, Brorby G. 2015. The role of the toxicologist in required food safety plans:  A case study of ochratoxin A (OTA) in coffee. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

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Proctor D, Suh M, Thompson C, Hixon, G. 2015. Inhalation cancer risk assessment of titanium dioxide. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

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Urban JD, Thompson CM, Plunkett LM, Perry CS, Haws LC. 2015. A state of the science copper reference dose for soil remediation. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

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Harris MA, Thompson CM, Proctor DM, Suh M, Wolf JC, Seiter JM, Chappell MA, Haws LC. 2015. Analysis of duodenal crypt health following exposure to Cr(VI) in drinking water. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

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Thompson CM, Young RR, Suh M, Dinesdurage H, Elbekai R, Harris MA, Rohr AC, Proctor DM. 2015. Hexavalent chromium does not induce mutations in the oral mucosa of transgenic Big Blue® rats following drinking water exposures at a carcinogenic dose. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

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Thompson CM, Suh M, Hixon G, Bichteler A. 2015. Comparison of smoothing spline regression and conventional modeling approaches for quantitative risk sssessments of human dioxin exposure. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

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Borghoff SJ, Wikoff D, White MC, Thompson C, Haws LC. 2015. Identification of the molecular initiating event (MIE) for TBBPA induced uterine tumors in the framework of an adverse outcome pathway (AOP). Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

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Wikoff D, White MC, Borghoff SJ, Haws LC. 2015. Evaluation of tetrabromobisphenol A (TBBPA)-induced endocrine-related target gene activity using high-throughput screening data from ToxCast. Presented at the Society of Toxicology’s 54th Annual Meeting, March 22-26, San Diego, CA.

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2014

Borghoff SJ, Hard GC, Poet TS, Davis J, Green S, Hughes B, Mensing T, Sarang SS. 2014. Methyl isobutyl ketone (MIBK) induces an exposure-related increase in measures of a2u-globulin (a2u) nephropath in male but not female F344 rats. Presented at the Society of Toxicology’s 53rd Annual Meeting, March 23-27, Phoenix, AZ.

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Haws LC, Thompson C, Perry C, White M, Fitzgerald L, Borghoff S, Wikoff D. 2014. Development of non-cancer based toxicity factors and daily dose estimates for TBBPA. Presented at the Society of Toxicology’s 53rd Annual Meeting, March 23-27, Phoenix, AZ.

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Kirman CR, Proctor D, Suh M, Thompson CM, Harris MA, Haws LC, Hays SM. 2014. Variation analysis of PBPK model parameters for describing the delivery of Cr(VI) to the small intestines of humans. Presented at the Society of Toxicology’s 53rd Annual Meeting, March 23-27, Phoenix, AZ.

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Hays SM, Kirman CR, Suh M, Proctor DM.  2014. Gastric reduction of hexavalent chromium [Cr(VI)] in fed and fasted human stomach samples. Presented at the Society of Toxicology’s 53rd Annual Meeting, March 23-27, Phoenix, AZ.

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Henderson R, Verougstraete V, Anderson K, Arbildua JJ, Brock TO, Brouwers T, Cappellini D, Delbeke K, Herting G, Hixon G, Odnevall Wallinder I, Rodriguez PH, Van Assche F, Wilrich P, Oller AR. 2014. Inter-laboratory validation of bioaccessibility testing for metals. Presented at the Society of Toxicology’s 53rd Annual Meeting, March 23-27, Phoenix, AZ.

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Hixon JG, Thompson C, Bichteler A, Abraham L. 2014. Smoothing regression splines as the basis for dose-response modeling. Presented at the Society of Toxicology’s 53rd Annual Meeting, March 23-27, Phoenix, AZ.

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Proctor DM, Suh M, Tachovsky JA, Abraham L, Hixon JG, Brorby GP, Campleman SL. 2014. Cumulative risk assessment of urban air toxics: A pilot study in San Antonio, Texas. Presented at the Society of Toxicology’s 53rd Annual Meeting, March 23-27, Phoenix, AZ.

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Suh M, Yzenas JJ, Proctor DM. 2014. Evaluation of electric arc furnace-processed steel slag for dermal corrosion, irritation, and sensitization. Presented at the Society of Toxicology’s 53rd Annual Meeting, March 23-27, Phoenix, AZ.

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Thompson CM, Proctor DM, Suh M, Wolf JC, Haws LC, Seiter JM, Chappell MA, Harris MA. 2014. X-ray fluorescence microspectroscopic analysis of duodenal mucosae following Cr(VI) exposure in drinking water. Presented at the Society of Toxicology’s 53rd Annual Meeting, March 23-27, Phoenix, AZ.

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Urban JD, Doepker CL, Cuellar-Kingston N, van de Ligt J, Carakostas M. 2014. Do highly purified steviol glycoside sweeteners cause food allergies? Presented at the Society of Toxicology’s 53rd Annual Meeting, March 23-27, Phoenix, AZ.

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Wikoff, D., Thompson, C., Perry, C., White, M., Fitzgerald, L., Borghoff, S., Haws, L.C. Development of an oral cancer slope factor and lifetime average daily dose estimates for TBBPA. Presented at the Society of Toxicology’s 53rd Annual Meeting, March 23-27, 2014. Phoenix, AZ.

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2013

Henderson R, Verougstraete V, Anderson K, Arbildua JJ, Brock TO, Brouwers T, Cappellini D, Delbeke K, Herting G, Hixon G, Odnevall Wallinder I, Rodriguez PH, Van Assche F, Wilrich P, Oller AR. 2013. Interlaboratory comparison of bioaccessibility tests for metals. Annual meeting of the Belgian Society for Toxicology and Ecotoxicology (BelTox).

Lamm SH, Britt JK, James RC. 2013. Multiple myeloma risk and benzene exposure among pliofilm workers – A re-analysis using an internal reference group. Presented at the Society of Toxicology’s 52nd Annual Meeting, March 10-14, San Antonio, TX.

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Wikoff D, Fitzgerald L, Haws L, Harris M. 2013. Health-based framework for evaluating the safety of hydraulic fracturing products. Presented at the Society of Toxicology’s 52nd Annual Meeting, March 10-14, San Antonio, TX.

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Suh M, Thompson CM, Hixon JG, Harris MA, Kirman CR, Hays S Haws LC, Proctor DM. 2013. Potential involvement of oxidative stress and iron disturbance in the development of oral cavity tumors in rats exposed to hexavalent chromium. Presented at the Society of Toxicology’s 52nd Annual Meeting, March 10-14, San Antonio, TX.

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Haws L, Hixon G, DeVito M, Walker N, Kuriakose L, Harris M, Birnba0um L, Wikoff D. 2013. Development of weighted distributions of relative potency estimates for dioxin-like compounds. Presented at the Society of Toxicology’s 52nd Annual Meeting, March 10-14, San Antonio, TX.

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Urban JD, Thompson CM, Deskin R, Waite M, Haws LC. 2013. Development of an oral cancer slope factor for acrylamide based on tumors relevant to humans. Presented at the Society of Toxicology’s 52nd Annual Meeting, March 10-14, San Antonio, TX.

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Thompson CM, Kirman CR, Proctor DM, Suh M, Hays SM, Haws LC, Harris MA. 2013. A chronic oral reference dose for hexavalent chromium. Presented at the Society of Toxicology’s 52nd Annual Meeting, March 10-14, San Antonio, TX.

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Proctor DM, Suh M, Thompson CM, Harris MA. 2013. Mode of action evaluation for hexavalent chromium-induced lung cancer. Presented at the Society of Toxicology’s 52nd Annual Meeting, March 10-14, San Antonio, TX.

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Kirman CR, Thompson CM, Proctor DM, Suh M, Haws LC, Harris MA, Hays SM. 2013. Using PBPK modeling to address diurnal variation and age differences in hexavalent chromium toxicokinetics in humans. Presented at the Society of Toxicology’s 52nd Annual Meeting, March 10-14, San Antonio, TX.

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2012

Brorby G, Proctor D, Perry C, Fitzgerald L, Tachovsky A. 2012. Probabilistic risk assessment of human exposure to iron and steel slag. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

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Finch G, Mounho B. 2012. Development of biosimilar products: Overview of standards and regulations. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

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Harris MA, Thompson CM, Wolf JC, Fedorov Y, Hixon JG, Proctor DM, Suh M, Haws LC. 2012. Assessment of genotoxic potential of Cr(VI) in the intestine via in vivo intestinal micronucleus assay and in vitro high content analysis in differentiated and undifferentiated caco-2. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

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Haws L, Fitzgerald L, Burkhalter K, Wikoff D. 2012. US EPA’s proposed toxicity values for TCDD: Implications for decision-making regarding the safety of foods in the United States. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

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Hays SM, Kirman C, Aylward L, Suh M, Proctor D. 2012. Gastric reduction of Cr(VI) in mice, rats and humans. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

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Hixon JG, Proctor D. 2012. Use of constrained logistic regression models for the dose-response analysis of beryllium sensitization and chronic beryllium disease with mean exposure. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

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Kim S, Kopec A, Forgacs AL, Thompson CM, Zacharewski T. 2012. Genome-wide gene expression analysis of Cr(VI) effects in Fisher rat small intestinal epithelium. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

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Kirman CR, Hays SM, Aylward LL, Suh M, Proctor D. 2012. Physiologically-based pharmacokinetic model for mice, rats and humans orally-exposed to chromium. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

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Kopec A, Forgacs AL, Kim S, Thompson CM, Zacharewski T. 2012. Comparative toxicogenomic analysis of Cr(VI) effects in rat and mouse small intestine. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

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Mounho B. 2012. Overview of the history and development of regional guidelines for the approval of biosimilar products. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

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O’Brien TJ, Hao D, Suh M, Proctor D, Thompson CM, Harris MA, Parsons BL, Meyers MB. 2012. K-ras codon 12 GGT to GAT mutation is not elevated in the duodenum of mice subchronically exposed to hexavalent chromium in drinking water. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

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Perry C, Tachovsky JA, Ke M, Urban J, Haws L. 2012. Natural gas exploration and production in the Barnett Shale: Assessment of exposures to volatile organic compounds (VOCs). Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

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Proctor DM, Thompson CM, Suh M, Haws LC, Harris MA. 2012. Mode of action for intestinal carcinogenesis of ingested hexavalent chromium in mice. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

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Thompson CM, Hixon JG, Kopec AK, Harris MA, Proctor DM, Haws LC. 2012. Assessment of genotoxic potential of Cr(VI) in the mouse duodenum via toxicogenomic profiling. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

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Urban J, Rowlands JC, Budinsky R, Dombkowski A, Thompson CM, Thomas RS. 2012. A genomics-based benchmark dose analyses of relative potencies of dioxin-like compounds in primary rat hepatocytes. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

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Wikoff D, DeVito M, Walker N, Hixon G, Harris M, Tachovsky A, Birnbaum L, Haws L. 2012. Application of machine learning in the development of a weighting framework for evaluating eEstimates of relative potency for dioxin-like compounds. Presented at the Society of Toxicology’s 51st Annual Meeting, March 11-15, San Francisco, CA.

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Mounho B. 2012. Regulatory standards for the approval of biosimilar products: A global review. Presented in Münster, Germany, May 23.

Mounho B. 2012. History and review of regulatory pathways for the approval of biosimilar products. Presented at Applied Pharmaceutical Toxicology Annual Meeting, May 17, Baltimore, MD.

2011

Thompson C, Perry C, Gaylor D, Tachovsky A, Burkhalter B, Haws L. 2011. Derivation of an oral reference dose and drinking water screening level for sulfolane using benchmark dose modeling. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, Washington, D.C.

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Mounho B. 2011. Definitions and standards for the approval of biosimilar products. Presented at American College of Toxicology Annual Meeting, November, Phoenix, AZ.

Urban J, Fitzgerald L, Burkhalter B, Staskal D, Harris M, Haws L. 2011. BTEX serum levels in the general U.S. population: An analysis of 2003-2004 NHANES dataset. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, Washington, D.C.

View Abstract

Diliberto JJ, Sirinek L, Burkhalter B, Wikoff DS, Hixon G, Becker J, Patterson DG, Turner W, Tachovsky JA, Birnbaum LS, Haws LC. 2011. Endometriosis in a cohort of women living in the Kanawha River Valley in West Virginia: Blood levels of non-dioxin-like PCBs and relationship with BMI and age. Presented at Dioxin 2011, August 21-25, Brussels, Belgium.

Oller A, Henderson RG. 2011. Bioaccessibility testing and its application to read-across for hazard assessment and risk characterisation of metals. Annual meeting of the Belgian Society for Toxicology and Ecotoxicology (BelTox).

Haws LC, DeVito MJ, Walker NJ, Harris MA, Tachovsky JA, Birnbaum LS, Farland WH, Wikoff DS. 2011. Development of a consensus-based weighting framework for evaluating estimates of relative potency for dioxin-like compounds that includes consideration of data from human cells. Presented at Dioxin 2011, August 21-25, Brussels, Belgium.

Semeraro A, Patriarca M, Taylor A, Henderson R, Bates H. 2011. Nickel kinetics after oral exposure: Urinary excretion. IUPAC 4th International Symposium for Trace Elements in Food.

Haws LC, Fitzgerald L, Burkhalter B, Harris M, Wikoff DS. 2011. Assessment of the US EPA’s proposed toxicological values for TCDD for regulation of dioxin-like compounds in foods: Bridging the science divide in a global market. Presented at Dioxin 2011, August 21-25, Brussels, Belgium.

Rowlands JC, Urban J, Wikoff DS, Budinsky R. 2011. The presence and estimated functional effect of single nucleotide polymorphisms at the AIP, ARNT, HSP90AA1, AND HSP90AB1 loci in the human population. Presented at Dioxin 2011, August 21-25, Brussels, Belgium.

Thomas RS, Rowlands JC, Budinsky RA, Thompson CM, Urban JD. Dombkowski, A. 2011. Genomic approaches for relative potency assessment. Presented at Dioxin 2011, August 21-25, Brussels, Belgium.

Wikoff DS, Thompson C, Walker N, DeVito M, Harris M, Birnbaum L, Haws L. 2011. Derivation of relative potency estimates using benchmark dose modeling: A case study with TCDF. Presented at Dioxin 2011, August 21-25, Brussels, Belgium.

Budinsky R, Urban J, Rowlands JC. 2011. An evaluation of single nucleotide polymorphisms in the human aryl hydrocarbon receptor nuclear translocator gene. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, Washington, D.C.

View Abstract

Ceder R, Merne M, Nilsson J-A, Staab C, Höög J-O, Thompson CM, Grafström RC. 2011.  Toxicogenomic profiling of formaldehyde-exposed normal and transformed human oral keratinocytes. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, Washington, D.C.

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Fitzgerald L, Burkhalter B, Urban J, Staskal D, Harris M, Haws L. 2011. VOC serum levels in the general U.S. population: An analysis of the 2003-2004 NHANES dataset. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, Washington, D.C.

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Haws L, Proctor D, Thompson C, Harris M. 2011. Research plan to fill data gaps in the mode of action for cancer risk assessment of hexavalent chromium in drinking water. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, Washington, D.C.

View Abstract

Henderson RG, Cappellini D, Seilkop S, Oller A, Bates H. 2011. Bioaccessibility-based read-across assessment of nickel compounds for oral systemic toxicity. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, Washington, D.C.

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Kim S, Thompson CM, Kopec AK, Harris MA, Zacharewski TR. 2011. Comparison of basal and CrVI-mediated solute carrier gene expression in rodent duodenal epithelium. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, Washington, D.C.

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Proctor D, Haws L,Thompson C, Harris M. 2011. Use of mode of action and pharmacokinetics to inform the cancer risk assessment of ingested Cr(VI): A case study. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, 2011. Washington, D.C.

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Proctor D, Meek B. 2011. Using mode of action data to guide quantitative cancer risk assessment: A case study of hexavalent chromium in drinking water. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, Washington, D.C.

View Abstract

Staskal-Wikoff D, Budinsky R, Rowlands JC. 2011. Single nucleotide polymorphisms in the human aryl hydrocarbon receptor interacting protein (AIP) gene from six ethnic populations. Presented at the Society of Toxicology’s 50th Annual Meeting, March 6-10, Washington, D.C.

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2010

Harris M, Tachovsky JA, Staskal-Wikoff D, Aylward L, Burkhalter B, Simon T, Haws L. 2010. Serum concentrations of dioxin-like compounds in a population in Midland, Michigan: An evaluation of the impact of soil exposures. Presented at Dioxin 2010, September 12-17, San Antonio, TX.

Harris M, Tachovsky JA, Staskal-Wikoff D, Simon T, Burkhalter B, Urban J, Haws L. 2010. Assessment of the impact of various soil cleanup levels on serum concentrations of dioxin-like compounds in humans. Presented at the 49th Annual Meeting of Society of Toxicology. March 7-11, Salt Lake City, Utah.

Haws L. 2010. Biomonitoring – A tool for assessing community exposures to air toxics. Presented at the Air Quality 2010 conference, hosted by the University of Texas School of Law,  November 19.

Haws L, Tachovsky JA, Staskal-Wikoff D, Aylward L, Burkhalter B, Urban J, Simon T, Harris M. 2010. An evaluation of the influence of different soil cleanup levels on the concentration of dioxin-like compounds in human serum. Presented at Dioxin 2010, September 12-17, San Antonio, TX.

Haws L. 2010. Biomonitoring: The circle of life. Presented in the Oil and Gas special session, at the 22nd Annual Texas Environmental Superconference, August 5-6, Austin, TX.

Staskal-Wikoff D, Burkhalter B, Stapleton H, Harris M. 2010. PBDEs in Newark Bay sediments. Presented at Dioxin 2010, September 12-17, San Antonio, TX.

Tachovsky JA, Haws L. 2010. Application of principal components analysis and sequential gaussian simulation to a comprehensive soil sampling dataset to predict PCDD/F concentrations in Midland, MI. Presented at Dioxin 2010, September 12-17, San Antonio, TX.

Mounho B. 2010. Safety evaluation of biotechnology derived products. Presented at Toxicology for Industrial and Regulatory Scientists, Sponsored by American College of Toxicology. April, Falls Church, VA.

Mounho, B. 2010. General review of the types of anti-drug antibody-mediated responses that can occur in toxicology studies. Presented at the 49th Annual Meeting of Society of Toxicology, March 7-11, Salt Lake City, Utah.

Tachovsky A, Staskal D, Urban J, Harris MA, Haws L. 2010. Assessment of environmental data collected in a community with numerous petroleum refining and petrochemical facilities. Presented at the 49th Annual Meeting of Society of Toxicology. March 7-11, Salt Lake City, Utah.

Tachovsky JA, Haws L. 2010. Geostatistical estimation of soil PCDD/F TEQ using sequential Gaussian simulation and the aggregation of results in Midland, MI. Presented at the Society for Risk Analysis annual meeting, December 5-8, Salt Lake City, UT.

Urban J, Burkhalter B, Tachovsky JA, Haws L, Harris M. 2010. Evaluation of polychlorinated naphthalenes (PCNs) in Newark Bay sediment. Presented at Dioxin 2010, September 12-17, San Antonio, TX.

2009

Haws LC, DeVito MJ, Walker NJ, Birnbaum LS, Farland WH, Harris MA, Tachovsky JA, Unice KM, Scott PK, Staskal-Wikoff DF. 2009. Development of distributions of relative potency estimates to quantitatively assess uncertainty inherent in the TEFs for dioxin-like compounds: A proposed consensus-based weighting. Presented at Dioxin 2009, Beijing, China.

Staskal-Wikoff DF, Harris MA, Haws LC, Birnbaum LS, Tachovsky JA. 2009. Probabilistic evaluation of cancer and non-cancer risk associated with exposure to BDE 209 in automobiles. Presented at Dioxin 2009. Beijing, China.

Urban JD, Tachovsky JA, Staskal DF, Haws LC, Harris MA. 2009. Human health risk assessment of consumption of fish from the Lower Passaic River. Presented at the 48th Annual Meeting of Society for Toxicology, March 15-19, Baltimore, MD.

Mounho B. 2009. Small molecule and biological therapeutics: History and inherent differences. Presented at Cambridge Healthtech Institute’s PEGS Summit, April 6-10, Boston, MA.

Mounho B. 2009. Preclinical toxicology studies to support the development of monoclonal abs: Scientific issues and challenges. Presented at Cambridge Healthtech Institute’s PEGS Summit, April 6-10, Boston, MA.

Mounho B. 2009. Scientific challenges in preclinical studies to support the clinical development of biologics. Presented at Cambridge Healthtech Institute’s Molecular Medicine Tri-Conference, February 25-27, San Francisco, CA.

Mounho B. 2009. Preclinical development of biologics. Presented at Cambridge Healthtech Institute’s Molecular Medicine Tri-Conference, February 25-27, San Francisco, CA.

Mounho B. 2009. Comparability challenges: Regulatory and scientific issues in the assessment of biopharmaceuticals. Presented at Drug Information Association Meeting.

Mounho B. 2009. Nonclinical safety assessment studies to support manufacturing process changes for Vectibix®. Presented at Drug Information Association Meeting.

2008

Harris MA, Shay E, Unice KM, Scott LF, Haws LC. 2008. Preliminary evaluation of health risks posed by PCDD/Fs and PCBs from the ingestion of fish from the Lower Passaic River. Presented at Dioxin 2008, August 17-22, Birmingham, England.

Harris MA, Tachovsky JA, Williams ES, Paustenbach DP, Haws LC. 2008. Assessment of the health risks posed by benzene in soft drinks. Presented at the Society of Toxicology Annual Meeting, March 16-20, Seattle, WA.

Haws LC, Unice KM, Tachovsky AT, Harris MA, DeVito MJ, WalkerNJ, Birnbaum LS, Farland WH, Nguyen L, Staskal DF. 2008. Assessment of the impact of using weighted distributions of REPs to develop exposure estimates for dioxin-like compounds. Presented at Dioxin 2008, August 17-22, Birmingham, England.

Haws LC, DeVito MJ, Walker NJ, Birnbaum LS, Unice KM, Scott PK, Harris MA, Tachovsky A, Farland WH, Finley BF,  Staskal DF. 2008. Development of weighted distributions of REPs for dioxin-like compounds: Implications for risk assessment. Presented at the Society of Toxicology Annual Meeting, March 16-20, Seattle, WA.

Scott LLF, Staskal DF, Harris MA, Finley BL, Haws LC. 2008. Evaluation of dioxin-like compounds in workers from a primary magnesium production facility relative to levels observed in the general US population. Presented at the Society of Toxicology Annual Meeting, March 16-20, Seattle, WA.

Staskal DF, Donovan EP, Haws LC, Roberts JD, Unice KM, Finley BL, Harris MA. 2008. Human health risks associated with exposure to pathogens in waters and sediments of the Lower Passaic River. Presented at the Society of Toxicology Annual Meeting. March 16-20, Seattle, WA.

Staskal DF. 2008. Roundtable: Case study on the risks and benefits of DecaBDE, a major brominated flame retardant. Presented at the Society of Toxicology Annual Meeting, March 16-20, Seattle, WA.

Staskal DF, Tachovsky JA, Harris MA, Haws LC. 2008. Preliminary evaluation of human health risk associated with exposure to PBDEs in the United States. Presented at Dioxin 2008, August 17-22, Birmingham, England.

Tachovsky JA, Harris MA, Staskal DF, Scott LF, Luksemburg WJ, Paustenbach DP, Haws LC. 2008. Analysis of fish tissue concentrations of dioxins and furans using principal components analysis. Presented at Dioxin 2008, August 17-22, Birmingham, England.

Tachovsky JA, Staskal DF, Harris MA, Scott LF, Luksemburg WJ, Paustenbach DP, Haws LC. 2008. Principal components analysis of PBDE concentrations in fish tissue from southern Mississippi. Presented at Dioxin 2008, August 17-22, Birmingham, England.

Urban JD, Haws LC, Staskal DF, Scott LF, Scott PS, Tachovsky AT, Unice KM, Harris MA. A framework for evaluating serum dioxin data derived from biomonitoring studies. Presented at Dioxin 2008, August 17-22, 2008. Birmingham, England.

Urban JD, Haws LC, Scott LF, Scott PS, Staskal DF, Tachovsky AT, Unice KM, Harris MA. 2008.A framework for evaluating serum dioxin data derived from biomonitoring studies. Presented at the Society of Toxicology Annual Meeting. March 16-20, Seattle, WA.

Williams CW, Perry CS. 2008. Risk assessment for arsenic on indoor surfaces. Presented at the Society for Risk Analysis annual meeting, December 7-10, Boston, MA.

2007

DeSesso, J., R.E. Watson, C.L. Keen, K.P. Hazleden, L.C. Haws, and A.A. Li. 2007. Integration of Developmental Toxicity Data into Risk Assessment: A Case Study of Dimethoate. Society of Toxicology. March 25-29, 2007. Charlotte, NC.

Diliberto, J.J., D.F. Staskal, H. Hakk, and L.S. Birnbaum. 2007. Differential Urinary Protien binding of PBDEs in Mice. Society of Toxicology. March 25-29, 2007. Charlotte, NC.

Dwyer, M., Perry, C., and Jenkins, A. Trichloroethylene toxicity and risks: recent developments and potential implications. Presented at February 2007 Texas Association of Environmental Professionals — Environmental Challenges and Innovations Conference.

Emond, C., J. Raymer, E. Garner, J. Diliberto, D. Staskal, and L.S. Birnbaum. 2007. A physiologically-based pharmacokinetic model for developmental exposure to PBDE-47 in rodents. Society of Toxicology. March 25-29, 2007. Charlotte, NC.

Ferriby, L.L., M.A. Harris, K.M. Unice, P.K. Scott, L.C. Haws, D.J. Paustenbach. 2007. Development of PCDD/F and dioxin-like PCB serum concentration reference values for the general U.S. population using the 2006 WHO TEFs and the 2001-2002 NHANES data.Society of Toxicology. March 25-29, 2007. Charlotte, NC.

Harris, M., L.L.F. Scott, L.M. Nguyen, and L.C. Haws. Trends in Elevated Blood Lead Levels of U.S. Children and Associated Demographic Characteristics. Ann Epidemiol. 17:748.

Harris, M., J.A.Tachovsky, E.S. Williams, L.L.F Scott, L. Nguyen, L.C. Haws. 2007. Risks Posed by Air Pollutants in the Houston Metropolitan Area. Society for Risk Analysis Annual Meeting. December 9-12, 2007. San Antonio, TX.

Harris, M., L.C. Haws, A. Tachosvky, E.S. Williams, L.M. Nguyen, L.F. Scott. Interactive Processes in Toxicity Assessments. Air Toxics Research: Implications of Research on Policies to Protect Public Health. June 12-13, 2007. Houston, TX.

Haws, L.C., L.L.F. Scott, D.F. Staskal, M.A. Harris, and B.L. Finley. 2007. Dioxin-like Compounds in Workers at a Primary Magnesium Production Facility. Dioxin 2007, September 2-7, 2007. Tokyo, Japan.

Haws, L.C., L.L.F. Scott, D.F. Staskal, M. Harris, and B. Finley. 2007. Evaluation of Biomonitoring Data for Dioxin-like Compounds in Workers at a Primary Magnesium Production Facility. Society for Risk Analysis Annual Meeting. December 9-12, 2007. San Antonio, TX.

Haws LC, Walker NJ, DeVito MJ, Birnbaum LS, Unice KM, Scott PK, Harris MA, Farland WH, Finley BL, Staskal DF. 2007. Development of weighted distributions of REPs for dioxin-like compounds (DLCs). Society of Toxicology Annual Meeting. March 25-29, Charlotte, NC.

Mounho, B. Comparison of Nonclinical Toxicology Programs for Epidermal Growth Factor Antagonists for Cancer Therapy: Monoclonal Antibodies Vectibix® and Erbitux® vs. Small Molecules Iressa® and Tarceva®. Presented at BioSafe General Membership Annual Meeting. 2007.

Mounho, B. Therapeutic Biologics. Presenter and course director: Biologics Drug Development: An Integrated Overview of Manufacturing, Nonclinical, Clinical, and Regulatory Requirements, PERI Course. Bethesda, MD. 2007.

Mounho, B. Nonclinical Safety Assessment of Therapeutic Biologics. Presenter and course director: Biologics Drug Development: An Integrated Overview of Manufacturing, Nonclinical, Clinical, and Regulatory Requirements, PERI Course. Bethesda, MD. 2007.

Nguyen, L.M., L.L.F. Scott, M. Harris, and L.C. Haws. Factors Contributing to Blood Lead Levels in U.S. Children Based on NHANES Data. 2007 Ann Epidemiol. 17:734-735.

Perry, C.S. Vibrios in surface waters and a hypothetical scenario using EPA’s Environmental Consequence Assessment Tool (ECAT). Society for Risk Analysis annual meeting, December 9-12, 2007. San Antonio, TX.

Scott, L.L.F., M. Harris, K.M. Unice, P. Scott, L.M. Nguyen, L.C. Haws, and D. Paustenbach. 2007. Effects of Excluding Serum PCDD/F and Dioxin-like PCB data of Individuals with Incomplete congener Profiles on Estimates of Total TEQ. Ann Epidemiol. 17:732.

Scott, P., L.C. Haws, L. Scott, and M. Harris. 2007. Evaluation of Background 2,3,7,8-PCDD/F Congener Profiles in Human Serum Collected During NHANES 2001-2002 Using Principal Components Analysis. Dioxin 2007, September 2-7, 2007. Tokyo, Japan.

Scott, P., L.C. Haws, L. Scott, and M. Harris. 2007. Evaluation of Background Dioxin-like PCB Congener Profiles in Human Serum Collected During NHANES 2001-2002 Using Principal Components Analysis. Dioxin 2007, September 2-7, 2007. Tokyo, Japan.

Smith, J.D., Perry C., Garcia, S., Jenkins, A., Dwyer, M., Garrahan, K. Emergency Consequence Assessment Tool (ECAT) for USEPA NHSRC. Society for Risk Analysis annual meeting, December 9-12, 2007. San Antonio, TX.

Staskal, D.F., E.P. Donovan, L.C. Haws, J.D. Roberts, K.M. Unice, B.L. Finley, and M.A. Harris. A Quantitative Microbial Risk Assessment for Exposure to Pathogens in Waters and Sediments of the Lower Passaic River. Society for Risk Analysis annual meeting, December 9-12, 2007. San Antonio, TX.

Staskal, D.F., L.L.F. Scott, E.S. Williams, W.J. Luksemburg, L.C. Haws, L.S. Birnbaum, L.M. Nguyen, D.J. Paustenbach, and M.A. Harris. Daily intake estimates of PBDEs associated with consumption of catfish in the U.S. Presented at the Fourth International Workshop on Brominated Flame Retardants. April 24-27, 2007. Amsterdam, the Netherlands.

Staskal, D.F., E. Donovan, J. Roberts, K. Unice, B. Finley, and M. Harris. 2007. Human Health Risk Associated with Exposure to Pathogen-Contaminated Sediments. Society of Toxicology. March 25-29, 2007. Charlotte, NC.

Tachovsky, J.A., L.C. Haws, L.F Scott, E.S. Williams, and M. Harris. Benzene in Soft Drinks and Other Beverages: Do Measured Levels Pose a Human Health Risk? Society for Risk Analysis’ Annual Meeting. December 9-12, 2007. San Antonio, TX.

Urban, J.D., K. Thornley, R.W. Wightman, and R.B. Mailman. 2007. Pharmacological characterization of the N27-D2L cell line: assessment as a viable cell model for investigating D2L receptor dopaminergic-coupled functions. Society of Toxicology. March 25-29, 2007. Charlotte, NC.

Williams, E.S., L.L. Ferriby, L.C. Haws, D.J. Paustenbach, and M.A. Harris. 2007. Assessment of potential human health risks posed by benzene in a commercial beverage. Society of Toxicology. March 25-29, 2007. Charlotte, NC.

2006

Ferriby, L.L., E.S. Williams, W.J. Lukesemburg, D.J. Paustenbach, L.C. Haws, L.S. Birnbaum, and M. Harris. 2006. Comparing Polychlorinated Biphenyls in Farm-Raised and Wild-Caught Catfish from Southern Mississippi. Organohalogen Compounds. 68: 2527-2530.  Dioxin 2006. August 21-25, 2006. Oslo, Norway.

Ferriby, L.L., E.S. Williams, W.J. Lukesemburg, D.J. Paustenbach, L.C. Haws, L.S. Birnbaum, and M. Harris. 2006. Comparing PCDDs, PCDFs, and Dioxin-Like PCBs in Farm-Raised and Wild-Caught Catfish from Southern Mississippi.  Dioxin 2006. August 21-25, 2006. Oslo, Norway.

Ferriby, L.L., K. Franke, K.M. Unice, P. Scott, L.C. Haws, M. Harris, and D.J. Paustenbach. 2006. Serum reference levels of PCDD/Fs and dioxin-like PCBs stratified by race/ethnicity, gender and age for the general U.S. population. American Public Health Association Annual Meeting and Exposition. November 4-8, 2006. Boston, MA.

Finster M., MacDonell, M., Bhattacharyya, M., Haroun L., Peterson J., and Perry, C. Environmental fate and cumulative risk context for cleanup programs. Society for Risk Analysis’ Annual Meeting. December 3-6, 2006. Baltimore, MD.

Gough, M., D. Paustenbach, B. Kerger, H. Leung, P. Scott, and M. Harris. 2006. Dioxin and diabetes does the current weight of evidence demonstrate a relationship. Society of Toxicology. March 5-9, 2006. San Diego, CA.

Harris, M., L. Ferriby, J. Knutsen, P. Nony, K. Unice, and D. Paustenbach. 2006. Evaluation of PCDD/F and dioxin-like PCB serum concentration data from the 2001-2002 National Health and Nutrition Examination Survey in the United States. Society of Toxicology. March 5-9, 2006. San Diego, CA.

Haws, L. The Use of Toxic Equivalency Factors to Assess Potential Human Health Risks Posed by Dioxin-like Compounds: Keeping Up With the Science. Presented at Michigan State University, Toxicology Program Seminar Series. September 26, 2006.

Haws, L.C., P.K. Scott, K.M. Unice, M. Gough, M.A. Harris, D.F. Staskal, D.J. Paustenbach, and M. Pavuk. Are Dioxin Body Burdens Surrogates for Other Risk Factors in Associations Between Dioxin and Diabetes?  Dioxin 2006. August 21-25, 2006. Oslo, Norway.

Haws, L.C., M.J. DeVito, L.S. Birnbaum, N.J. Walker, P.K. Scott, K.M. Unice, M.A. Harris, W.H. Farland, B.L. Finley, and D.F. Staskal. An Alternative Method for Establishing TEFs for Dioxin-like Compounds. Part 2. Development of An Approach To Quantitatively Weight the Underlying Potency Data. Dioxin 2006. August 21-25, 2006. Oslo, Norway.

Paustenbach, D.J., M.. Harris, L.L. Ferriby, E.S. Williams, L.C. Haws, K.M. Unice, and P.K. Scott. 2006. Development of PCDD/F TEQ serum reference values for the U.S. population for use in evaluating biomonitoring results. Dioxin 2006. August 21-25, 2006. Oslo, Norway.

Richardson, V.M., D.F. Staskal, J.J. Diliberto, and L.S.Birnbaum. 2006. Effects of BDE 47 on nuclear receptor regulated genes and implications for thyroid hormone disruption. 45th Annual Meeting of Society for Toxicology. March 5-9, 2006. San Diego, CA.

Scott, P.K., L.C. Haws, D.F. Staskal, L.S. Birnbaum, N.J. Walker, M.J. DeVito, M.A. Harris, W.H. Farland, B.L. Finley, and K.M. Unice. An Alternative Method for Establishing TEFs for Dioxin-like Compounds. Part 1. Evaluation of Decision Analysis Methods for Use in Weighting Relative Potency Data. Dioxin 2006. August 21-25, 2006. Oslo, Norway.

Staskal, D.F., K.M. Unice, N.J Walker, M.J. DeVito, L.S. Birnbaum, P.K. Scott, M.A. Harris, W.H. Farland, B.L. Finley, and L.C. Haws. An Alternative Method for Establishing TEFs for Dioxin-like Compounds. Part 3. Development of Weighted Distributions of REPs for PCB126 and 2,3,4,7,8-PeCDF. Dioxin 2006. August 21-25, 2006. Oslo, Norway.

Staskal, D.F., L.L. Ferriby, E.S. Williams, W.J. Luksemburg, L.C. Haws, L.S. Birnbaum, D.J. Paustenbach, and M. Harris. 2006. Polybrominated diphenyl ethers in southern Mississippi catfish. Dioxin 2006. August 21-25, 2006. Oslo, Norway.

Staskal, D.F., J.J. Diliberto, and L.S. Birnbaum. 2006. Effect of age on the tissue distribution of BDE 47 in mice. 45th Annual Meeting of Society for Toxicology. March 5-9, 2006. San Diego, CA.

Urban, J.D., J. Jin, and R.B. Mailman. 2006. N27 dopaminergic cell line: A useful model for studying the mechanisms of action of functionally selective dopaminergic compounds. 45th Annual Meeting of Society for Toxicology. March 5-9, 2006. San Diego, CA.

Van den Berg, M., L. Birnbaum, M. Denison, M. De Vito, W. Farland, M. Feeley, H. Fiedler, H. Hakansson, A. Hanberg, L.C. Haws, M. Rose, S. Safe, D. Schrenk, C. Tohyama, A. Tritscher, J. Tuomisto, M. Tysklind, N. Walker, and R.E. Peterson. 2006. Human And Mammalian Toxic Equivalency Factors For Dioxins And Dioxin-like Compounds: The WHO 2005 Re-Evaluation.  Dioxin 2006. August 21-25, 2006. Oslo, Norway.

Paustenbach, D.J., L.L.F. Scott, L.M. Nguyen, K.M. Unice, P. Scott, L.C. Haws, and M. Harris. 2007. Referent Concentrations of PCDD/Fs and Dioxin-like PCBs in Sera of Persons in the U.S. Based on the New WHO 2006 TEFs and 2001-2002 NHANES Data. Ann Epidemiol. 17:734.

Mounho, B. Chronic Toxicity Studies for Monoclonal Antibodies: Avastin® and Erbitux®. Presented at BioSafe/FDA meeting. 2006.

Mounho, B. The Use of Toxicokinetics and Toxicodynamics in the Safety Assessment and Development of Small and Large Molecule Therapeutic Products. Presenter and Symposium Chair: American College of Toxicology Annual Meeting. 2006.

Mounho, B. Immunomodulation in Nonhuman Primates. Presented at Pharmaceutical Education Associates Immunotoxicology IV Meeting. 2006.

2005

Bauer, D., D.F. Staskal, J.J. Diliberto, and L.S. Birnbaum. 2005. Disposition of BDE 99 and BDE 153 in female mice. Society of Toxicology. March 6-10, 2005. New Orleans, LA.

Connor, K., M. Harris, M. Edwards, A. Chu, G. Clark, and B. Finley. 2004. Estimating the total TEQ in human blood from naturally-occurring vs. anthropogenic dioxins: a dietary study.  DIoxin 2005. August 21-26, 2005. Toronto, Canada.

Harris, M., and B. Finley. Estimating the total TEQ in human blood from naturally-occurring vs. anthropogenic dioxins: a dietary study. Society of Toxicology. March 6-10, 2005. New Orleans, LA.

Harris, M., B. Finley, P. Scott. Development of a Relative Estimate of Potency Distribution for 2,3,7,8-TCDF. Dioxin 2005. August 21-26, 2005. Toronto, Canada.

Haws, L. Evaluating Potential Health Risks Posed By PCDDs, PCDFs, and Dioxin-like PCBs: An Approach for Improving the Toxicity Equivalency Factor (TEF) Methodology. 30th Annual Winter Meeting of the Toxicology Forum. February 2, 2005. Washington, DC.

Mounho, B. Differences Between Small Molecules and Biological Therapeutic Drug Products. Society of Toxicology. March 6-10, 2005. New Orleans, LA.

Paustenbach, D.J., K. Fehling, M. Harris, P. Scott, B.D. Kerger. Identifying a Soil Clean-up Criteria for Dioxin in Residential Soils: How Has 20 Years of Research and Risk Assessment Experience Impacted The Analysis? DIoxin 2005. August 21-26, 2005. Toronto, Canada.

Perry, C.S., Garcia, S., Collie, S., MacDonell, M., Femi Adeshina, and Cynthia Sonich-Mullin: Application of provisional advisory levels for EPA National Homeland Security Research Center’s secure, internet-based rapid risk tool. Society for Risk Analysis’ Annual Meeting. December 4-7, 2005. Orlando, FL.

Urban, J.D. and R.B. Mailman. 2005. Characterization of the N27 dopaminergic cell line as a model for elucidating the actions of functionally selective dopaminergic ligands. 35th Annual Neuroscience Meeting. November 12-16, 2005. Washington, DC.

Grasty RC, N Roberts, G Klinefelter, JA Bjork, KB Wallace, CS Lau, and JM Rogers (2005). Effects of prenatal perfluorooctanesulfonate (PFOS) exposure on lung maturation in the perinatal rat. Birth Defects Res A Clin Mol Teratol 73: 314.

2004

Connor, K., M. Harris, M. Edwards, A. Chu, G. Clark, and B. Finley. 2004. Estimating the total TEQ in human blood from naturally-occurring vs. anthropogenic dioxins: a dietary study.  Dioxin 2004. September 6-10, 2004. Berlin, Germany.

Haws, L. Roundtable: Is it Time to Reevaluate the Toxic Equivalency Factors for PCDDs, PCDFs, and Dioxin-Like PCBs? The Use of Toxicity Equivalence Factors (TEFs) for PCDDs, PCDFs, and Dioxin-Like PCBs in Risk Assessment: Improving the Process. Dioxin 2004. September 6-10, 2004. Berlin, Germany.

Haws, L., M. Harris, S. Su, L. Birnbaum, M. DeVito, W. Farland, N. Walker, K. Connor, A.Santamaria, and B. Finley. Development of a refined database of relative potency estimates to facilitate better characterization of variability and uncertainty in the current mammalian TEFs for PCDDs, PDCFs, and dioxin-like PCBs. Dioxin 2004. September 6-10, 2004. Berlin, Germany.

Haws, L., M. Harris, S. Su, N. Walker, L. Birnbaum, M. DeVito, W. Farland, K. Connor, A. Santamaria, and B. Finley. A preliminary approach to characterizing variability and uncertainty in the mammalian PCDD/F and PCB TEFs. Dioxin 2004. September 6-10, 2004. Berlin, Germany.

Perry, C.S. and Morton, E. Lessons learned from creating integrated Excel models to calculate human health screening values. Society for Risk Analysis’ Annual Meeting. December 5-8, 2004. Palm Springs, CA.

Staskal, D.F., J.J. Diliberto, M.J. DeVito, and L.S. Birnbaum. 2004. Tissue distribution and elimination of BDE 47 in mice following a single oral dose.  Dioxin 2004. September 6-10, 2004. Berlin, Germany.

Staskal, D.F., J.J. Diliberto, M.J. DeVito, and L.S. Birnbaum. 2004. Disposition of 2,2’,4,4’-Tetrabromodiphenylether (BDE 47) in Female Mice. 43rd Annual Meeting of Society for Toxicology. March 21-25, 2004. Baltimore, MD.

Urban, J.D., E.A.Gay, and R.B. Mailman. 2004. Functional selectivity as a mechanism of action of newer atypical antipsychotic drugs. 34th Annual Neuroscience Meeting. October 23-27, 2004. San Diego, CA.

Grasty RC, Roberts N, Grey BE, Lau C, Rogers JM. (2004). Effects of prenatal exposure to perfluorooctane sulfonate on the developing lung in the rat. 43rd Annual Meeting of Society for Toxicology. March 21-25, 2004. Baltimore, MD.

Urban, J.D., E.A. Gay, and R.B. Mailman. 2004. Decreased neurological side-effects with aripiprazole: a result of functional selectivity of the D2 receptor? 43rd Annual Meeting of Society for Toxicology. March 21-25, 2004. Baltimore, MD.

Grasty RC, Roberts N, Grey BE, Lau C, Rogers JM. (2004). Perfluorooctane sulfonate (PFOS) alters lung development in the neonatal rat. Birth Defects Research, Part A, 70(5), 42.

2003

Haws, L. Combustion Risk Modeling and Assessment. Presented at the Texas Commission on Environmental Quality Workshop on Hazardous Waste Combustion. May 7, 2003. Austin, TX.

Perry, C.S. Process for development of protective concentration levels for remediation sites in Texas.Presented at Society for Environmental Toxicology and Chemistry (SETAC) meeting. November 9-13, 2003. Austin, TX.

Staskal, D.F., M.J. DeVito, D.G. Ross, and L.S. Birnbaum. 2003. A Comparison of the metabolism of methoxyresorufin, acetanilide, and caffeine in rat and human CYP1A2 SUPERSOMES. The Toxicologist.

Staskal, D.F., M.J. DeVito, D.G. Ross, and L.S. Birnbaum. 2003. Caffeine, Acetanilide, and Methoxyresorufin Metabolism by Rat and Human CYP1A2 SUPERSOMES and their Inhibition by 2,3,7,8,-Tetrachlorodibenzo-p-dioxin (TCDD). Organohalogen Compounds.

Grasty RC, Grey BE, Lau CS, Rogers JM. 2003. Window of susceptibility to perfluorooctane sulfonate (PFOS)-induced neonatal mortality in the rat. Birth Defects Research, Part B, 68(3), 5.

Lansita, JA, Merok, JR, and Sherley, JL. 2003. “Physicochemical Demonstration of Immortal DNA Strand Segregation,” in “Mechanisms of Toxicity, Carcinogenesis, Cancer Prevention and Cancer Therapy: Abstracts of the Seventeenth Aspen Cancer Conference,” Tox. Path., 31, 163-164.

Merok, JR, Tunstead, JR, Lansita, JA, and Sherley, JL. 2003. “Demonstration of an Immortal DNA Strand Mechanism in Cells That Cycle with Asymmetric Stem Cell Kinetics-Implications for Mechanisms of Human Cancer and Aging,” in “Mechanisms of Toxicity, Carcinogenesis, Cancer Prevention and Cancer Therapy: Abstracts of the Seventeenth Aspen Cancer Conference,” Tox. Path., 31, 165-166.

2002

Haws, L. Permitting of Hazardous Waste Combustion Facilities in the State of Texas: Human Health Risks Associated with Fugitive Emissions Sources. Presented at the Texas Chemical Council Quarterly Meeting. August 1, 2002. Houston, TX.

Haws, L. Texas Risk Reduction Program Rule-The Basics. Question and Answer Forum Panelist. Presented at the Texas Natural Resource Conservation Commission Environmental Trade Fair. Waste Remediation Track. May 7, 2002. Austin, TX.

Haws, L. Toxicology and Risk Assessment Resources and Practices in the State of Texas. Presented at the USEPA Region 6 States Risk Assessment Roundtable. April 5, 2002. Dallas, TX.

Perry, C.S. TRRP Rule – The basics part 2: human health PCLs and look-up tables. 2002 TNRCC Environmental Trade Fair presentation and paper.

Grasty RC, Grey BE, Thibodeaux J, Lau C, Rogers JM. (2002). Critical period for increased neonatal mortality induced by perfluorooctane sulfonate (PFOS) in the rat. The Toxicologist 66 (1-S), 118.

Staskal, D.F., M.J. DeVito, D.G. Ross, and L.S. Birnbaum. 2002. Inhibition of human and rat CYP1A2 by TCDD and dioxin-like chemicals. The Toxicologist.

2001

Haws, L. Risk Assessment Coordination Between EPA and States Panelist. Presented at the USEPA Regional Risk Assessors Annual Conference. May 25, 2001. Bandera, TX.

Haws, L. Texas Risk Reduction Program Rule-Practical Applications. Question and Answer Forum Panelist. Presented at the Texas Natural Resource Conservation Commission Environmental Trade Fair. Waste Remediation Track. April 30, 2001. Austin, TX.

Skaggs, Jr. M.M., and M. Harris. 2001. A management trend: towards special remedial organizations. SPE/EPA/DOE Exploration and Production Environmental Conference. February 26-28, 2001. San Antonio, TX.

Tachovsky, J. A., J. T. McCoy, and L. C Haws. Development and implementation of probabilistic risk assessment protocol in Texas. Presented at the 94th Conference of the AWMA. June 24-28, 2001. Orlando, FL.

2000

Grant, R.L., D. Morrill, D. Manis, A. Tachovsky, and L.C. Haws. 2000. The Texas combustion project: review of trial burn/risk burn plans and reports. Proceedings, International Conference on Incineration and Thermal Treatment Technologies. May 8–12, 2000. Portland, OR.

Tachovsky, J.A., L.C. Haws, C.S. Hofelt, and J.T. McCoy. 2000. Risk assessment implementation in Texas. Proceedings, International Conference on Incineration and Thermal Treatment Technologies. May 8–12, 2000. Portland, OR.

Urban, J.D. and R.B. Mailman. 2005. Functional selectivity as a mechanism of action for newer atypical antipsychotic drugs. Presented at: Merck, West Point, Pennsylvania, USA.

1999

Haws, L. Permitting of Hazardous Waste Combustion Facilities in the State of Texas: Risk Assessment Procedures and Status Update. Presented at the Texas Chemical Council Quarterly Meeting. September 15, 1999. Houston, TX.

1998

Harris, M., and M.M. Skaggs. A review of chromium treatment technologies, YPF Environmental Congress. September 1998. Buenos Aires, Argentina.

Fraiser, L.H., J.A. Tachovsky, M.E. King, J.T. McCoy, and L.C. Haws. 1998. Hazardous waste combustion risk assessment experience in the state of Texas. Proceedings, International Conference on Incineration and Thermal Treatment Technologies Conference. May 11–15, 1998. Salt Lake City, UT.

1997

Skaggs, Jr. M.M., and M.A. Harris. 1997. Risk management strategies for site closure actions. National Association for Environmental Management. October 1997. Dallas, TX.

1996

Fraiser, L.H., L.G. Lund, K.H. Tyndall, M.E King, D.A. Schultz, and L.C. Haws. 1996. Case Studies in risk assessment for hazardous waste burning cement kilns. Air and Waste Management Association Specialty Conference. Waste Combustion in Boilers and Industrial Furnaces. March 25-26, 1996. Kansas City, MO.

Lund, L.G., L.C. Haws, J.T. McCoy, L.C. Carlisle, D. Brymer, D. Thompson, and J.M. Wiersema. 1996. Addressing community concerns about industrial emissions and burning of hazardous waste in cement kilns: a summary of environmental data. Air and Waste Management Association Specialty Conference. Waste Combustion in Boilers and Industrial Furnaces. March 25-26, 1996. Kansas City, MO.

McCoy, J.T., L.C. Haws, L.C. Carlisle, J.M. Wiersema, D. Carmichael, D., and S. Mgebroff. 1996. Soil sampling and analysis for PCDDs/PCDFs Downwind of combustion sources in six Texas communities. Society of Environmental Toxicology and Chemistry Annual Meeting Abstract Book.

1995

Fraiser, L.H., L.G. Lund, K.L. Hueske, and L.C. Haws. 1995. Indirect risk assessment: case studies of hazardous waste combustors. Society of Toxicology Annual Meeting. March 5-9, 1995. Baltimore, MD. The Toxicologist 30:31

1994

Haws, L. How Are We Implementing the Combustion Strategy and Indirect Risk Assessment? Presented at the Texas Natural Resource Conservation Commission Hazardous Waste Seminar. October 26-27, 1994. Houston, TX.

Haws, L. Indirect Risk Assessment. Presented at the Sixth Annual Texas Environmental Superconference. August 4-5, 1994. Austin, TX.

Haws, L. Overview of TNRCC/EPA Concerns, Strategies, and Schedules Concerning Indirect Risk Assessment Requirements. Presented at the Workshop on Risk Assessment and Waste Incineration Facilities. June 28, 1994, Houston, TX, and June 29, 1994. Austin, TX.

Haws, L. Indirect Risk Workshop. Panel Discussant. Presented at the RCRA Policy Forum. January 31, 1994. Washington, DC.

Haws, L. Keynote Address. Presented at the DRE Environmental Services Workshop on EPA’s New Policy of Hazardous Waste Combustion. January 21, 1994. Austin, TX.

1993

Haws, L. Principles of Toxicology and Risk Assessment. Presented at the University of Texas at Austin. LBJ School of Public Affairs. September 10, 1993. Austin, TX.

1992

Haws, L. Developmental Toxicity of TCDD and Related Compounds. Presented at the Texas A&M University Faculty of Toxicology Seminar Series. October 12, 1992. College Station, TX.

Wenning, R.I., D.J. Paustenbach, M.A. Harris, H. Bedbury. Chemometric Analysis of Potential Sources of Polychlorinated Dibenzo-p Dioxin and Dibenzofuran Residues in Surficial Sediments from Newark Bay, New Jersey. Dioxin 1992. August 24-28, 1992. Tampere, Finland.

Wenning, R.I., D.J. Paustenbach, M.A. Harris, H. Bedbury. Sources of PCDD/Fs in Newark Bay Sediments. 13th Annual Meeting of the Society of Environmental Toxicology and Chemistry. November 8-12, 1992. Cincinnati, OH.

1991

Arrellano, L., M. Harris, and S. Safe. 1991. Induction of Cypiai Gene transcription by TCDD in MDA-MB-231 human breast cancer cells. Society of Toxicology 30th Annual Meeting. February 25-March 1, 1991. Dallas, TX.

Copeland, T., M. Harris, B. Finley, and D. Paustenbach. 1991. Health effects and environmental characterization of Octachlorodibenzo-p-dioxin (OCDD): Impact on risk assessment of former wood treatment sites. Society of Toxicology 30th Annual Meeting. February 25-March 1, 1991. Dallas, TX.

Fernandez, P., M. Harris, and S. Safe. 1991. Effects of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) on T47-D human breast cancer cell lines. Society of Toxicology 30th Annual Meeting. February 25-March 1, 1991. Dallas, TX.

Harris, M., L. Biegel, T. Zacharewski, S. and Safe, S. 6-methyl-1,3,8-trichlorodibenzofuran (MCDF) as an antiestrogen: effects on nuclear estrogen receptor levels, cell growth and the 17_-Estradiol-induced secretion of proteins in MCF-7 Cells. Society of Toxicology 30th Annual Meeting. February 25-March 1, 1991. Dallas, TX.

Harris, M., B. Finley, R. Wenning, and D. Paustenbach. 1991. Evaluation of Potential Sources of 1,2,8,9-TCDD in Aquatic Biota from Newark Bay. Society of Toxicology 30th Annual Meeting. February 25-March 1, 1991. Dallas, TX.

Jackson, B.A., L.C. Haws, R.J. Wixtrom, and T.B. Starr. 1991. Secondary mechanisms in carcinogenesis: breaking out of the no-threshold paradigm. American College of Toxicology Annual Meeting. Savannah, Georgia.

Piskorska-Pliszczynska, J., B. Astroff, T. Zacharewski, M. Harris, R. Rosengren, V. Morrison, L. Safe, and S. Safe. 1991. Mechanism of action of 2,3,7,8-Tetrachlorodibenzo-p-dioxin Antagonists: characterization of [125I]-6-methyl-8-Iodo-1,3-dichlorodibenzofuran-Ah receptor complexes. Society of Toxicology 30th Annual Meeting. February 25-March 1, 1991. Dallas, TX.

1990

Couture, L.A., M.W. Harris, A.M. Clark, and L.S. Birnbaum. 1990. Persistence of hydronephrosis in mice following in utero and/or lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Society of Toxicology Annual Meeting. February 12-16, 1990. Miami Beach, FL. The Toxicologist. 10:313.

Harris, M., R. Wenning, B. Finley, and D. Paustenbach. 1990. Evaluation of potential sources of 1,2,8,9-TCDD in aquatic biota from Newark Bay. Society of Environmental Chemistry and Toxicology. November 11-15, 1990. Washington, DC.

Harris, M., T. Zacharewski, S. and Safe, S. 2,3,7,8-Tetrachlorodibenzo-p-dioxin as an antiestrogen: Effects of nuclear estrogen receptor levels in MCF-7 Cells. Society of Toxicology Meeting. February 12-16, 1990. Miami Beach, FL.

Zacharewski, T., J. Piskorska-Pliszczynska, F. Rosengren, B. Astroff, M. Harris, L. Safe, and S.Safe. 1990. 8-Iodo-1,3-dichlorodibenzofuran (I-MCDF) and 125I-MCDF as a 2,3,7,8-Tetrachlordibenzo-p-dioxin (TCDD) antagonist. Society of Toxicology Meeting. February 12-16, 1990. Miami Beach, FL.

1989

Couture, L.A., M.W. Harris, and L.S. Birnbaum. Characterization of TCDD-induced hydronephrosis relative to cleft palate in C57BL/6N Mice. Presented at the Society of Toxicology Annual Meeting. February 27-March 3, 1989. Atlanta, GA.

Harris, M., M. Romkes, and S. Safe. Human Breast Cancer Cells as Models for Investigating Ah Receptor Mediated Processes. Dioxin ’89. September 17-22, 1989. Toronto, Canada.

Harris, M., M. Romkes, and S. Safe. Human breast cancer cells as models for investigating ah receptor mediated processes. Society of Toxicology 28th Annual Meeting. February 27-March 3, 1989. Atlanta, GA.

Zacharewski, T., M. Harris, and S. Safe. 1989. Structure dependent induction of aryl hydrocarbon hydroxylase of TCDD and related compounds: mechanistic studies. Society of Toxicology 28th Annual Meeting. February 27-March 3, 1989. Atlanta, GA.

Randerath, K., K.L. Putman, E. Randerath, M. Harris, T. Zacharewski, and S. Safe. Effects of 2,3,7,8-TCDD and related compounds on the levels of age-dependent i-spot DNA adducts in the liver of female and male Sprague-Dawley rats. Dioxin ’89. September 17-22, 1989. Toronto, Canada.

1988

Couture, L.A., M.W. Harris, and L.S. Birnbaum. Teratogenicity of 2,3,4,7,8-Pentachlorodibenzofuran (4-PeCDF) in F344 rats. Presented at the Society of Toxicology Annual Meeting. February 15-19, 1988. Dallas, TX.

Harris, M., T. Zacharewski, B. Astroff, C. Kamps, and S. Safe. Characterization of 6-Methyl-1,3,8-Trichlorodibenz-furan (MCDF) as a 2,3,7,8-TCDD Antagonist in Male Rats: Induction of Monooxygenases. Dioxin ’88 Symposium. August 21-26, 1988. Umea, Sweden.

Harris, M., C. Kamps, and S. Safe. Role of 4s binding protein in the induction of aryl hydrocarbon hydroxylase in the rat. Society of Toxicology 27th Annual Meeting. February 15-19, 1988. Dallas, TX

Zacharewski, T., M. Harris, and S. Safe. 1988. Validation of the in vitro bioassay: determination of 2,3,7,8-TCDD equivalents in pyrolyzed flame retardants and great lakes fish extracts. Gulf Coast Society of Toxicology and Southwest Environmental Mutagens Society Meeting. 1988. Houston, TX.

1987

Couture, L.A., and L.S. Birnbaum. Evaluation of Subchronic exposure to Octachlorodibenzodioxin (OCDD). Presented at the Society of Toxicology Annual Meeting. February 23-27, 1987. Washington, DC.

Kamps, C., M. Harris, and S. Safe. 1987. Polynuclear aromatic hydrocarbon—4s binding protein interactions. Structure activity relationships. Society of Toxicology 26th Annual Meeting. February 1987. Washington DC.

Safe, S., T. Zacherewski, M. Harris, C. Yao, and M. Holcomb. 1987. Validation of the AHH induction bioassay for the determination of 2,3,7,8-TCDD toxic equivalents. Dioxin ’87 Symposium. October 4-9, 1987. Las Vegas, NV.

Zacharewski, T., M. Harris, S. Safe, H. Thoma, G. Hauschulz, E. Knorr, and O. Hutzinger. 1987. Applications of the In vitro AHH induction bioassay for determining 2,3,7,8-TCDD equivalents: pyrolyzed flame retardant mixtures. Dioxin ’87 Symposium. October 4-9, 1987. Las Vegas, NV.

1986

Birnbaum, L.S., and L.A. Couture. 1986. Disposition of Octachlorodibenzo-p-dioxin (OCDD) in rats. Society of Toxicology Annual Meeting. March 3-7, 1986. New Orleans, LA. The Toxicologist. 6:310.